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    yeaG protein kinase YeaG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946297, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yeaG
    Official Full Name
    protein kinase YeaG
    Primary source
    ECOCYC:G6969
    Locus tag
    b1783
    See related
    ASAP:ABE-0005935
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1781
    Summary
    AFMB Structural Genomics target Number 55 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG13493]. YeaG is a member of the PrkA family of serine protein kinases. [More information is available at EcoCyc: G6969].
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    Genomic context

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    Sequence:
    NC_000913.3 (1866908..1868842)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene methylglyoxal reductase YeaE Neighboring gene MltA-interacting protein Neighboring gene DUF444 domain-containing protein YeaH Neighboring gene putative c-di-GMP binding protein CdgI

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel regulatory factor affecting the transcription of methionine biosynthesis genes in Escherichia coli experiencing sustained nitrogen starvation. Switzer A, et al. Microbiology (Reading), 2018 Nov. PMID 29957170
    2. EcID. A database for the inference of functional interactions in E. coli. Andres Leon E, et al. Nucleic Acids Res, 2009 Jan. PMID 19004873, Free PMC Article
    3. Identification of RpoS (sigma(S))-regulated genes in Salmonella enterica serovar typhimurium. Ibanez-Ruiz M, et al. J Bacteriol, 2000 Oct. PMID 11004173, Free PMC Article
    4. Genome-wide analysis of the general stress response network in Escherichia coli: sigmaS-dependent genes, promoters, and sigma factor selectivity. Weber H, et al. J Bacteriol, 2005 Mar. PMID 15716429, Free PMC Article
    5. Nitrogen regulatory protein C-controlled genes of Escherichia coli: scavenging as a defense against nitrogen limitation. Zimmer DP, et al. Proc Natl Acad Sci U S A, 2000 Dec 19. PMID 11121068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. this study identifies YeaG as a novel regulatory factor in E. coli affecting the transcription of methionine biosynthesis genes under sustained N starvation.
      Title: A novel regulatory factor affecting the transcription of methionine biosynthesis genes in Escherichia coli experiencing sustained nitrogen starvation.
    2. results indicate that yeaG is required to fully execute the rpoS-dependent gene expression program to allow E. coli to adapt to sustained N starvation and unravels a novel facet to the regulatory basis that underpins adaptive response to N stress.
      Title: Adaptation to sustained nitrogen starvation by Escherichia coli requires the eukaryote-like serine/threonine kinase YeaG.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to nitrogen starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to nitrogen starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein kinase YeaG
    NP_416297.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1866908..1868842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416297.1 protein kinase YeaG [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416297.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X1NJ11
      Conserved Domains (1) summary
      PRK15455
      Location:1 → 644
      PRK15455; PrkA family serine protein kinase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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