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    rfbD dTDP-4-dehydrorhamnose reductase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947117, updated on 3-Dec-2024

    Summary

    Official Symbol
    rfbD
    Official Full Name
    dTDP-4-dehydrorhamnose reductase
    Primary source
    ECOCYC:EG12411
    Locus tag
    b2040
    See related
    ASAP:ABE-0006764
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2034; rmlD
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    Genomic context

    Sequence:
    NC_000913.3 (2111077..2111976, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene polyisoprenol-linked O16-antigen repeat unit flippase Neighboring gene dTDP-4-dehydrorhamnose 3,5-epimerase Neighboring gene glucose-1-phosphate thymidylyltransferase 1 Neighboring gene dTDP-glucose 4,6-dehydratase 1 Neighboring gene UTP:glucose-1-phosphate uridylyltransferase, low activity Neighboring gene putative colanic acid biosynthesis protein WcaM

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables dTDP-4-dehydrorhamnose reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables dTDP-4-dehydrorhamnose reductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables dTDP-4-dehydrorhamnose reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within O antigen biosynthetic process EXP
    Inferred from Experiment
    more info
    PubMed 
    involved_in O antigen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in dTDP-rhamnose biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dTDP-rhamnose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lipopolysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lipopolysaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in polysaccharide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in polysaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    dTDP-4-dehydrorhamnose reductase
    NP_416544.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2111077..2111976 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416544.1 dTDP-4-dehydrorhamnose reductase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416544.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q3IA88
      Conserved Domains (1) summary
      PRK09987
      Location:1299
      PRK09987; dTDP-4-dehydrorhamnose reductase; Provisional