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    yfaE ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946729, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yfaE
    Official Full Name
    ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE
    Primary source
    ECOCYC:EG12360
    Locus tag
    b2236
    See related
    ASAP:ABE-0007390
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2228
    Summary
    Putative third gene in nrdAB-yfaE operon. [More information is available at EcoGene: EG12360]. YfaE is a [2Fe2S] cluster-containing protein that is involved in maintenance and possibly in the biosynthesis of active |FRAME: [More information is available at EcoCyc: EG12360].
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    Genomic context

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    Sequence:
    NC_000913.3 (2348514..2348768)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ribonucleoside-diphosphate reductase 1 subunit alpha Neighboring gene protein YoaM Neighboring gene ribonucleoside-diphosphate reductase 1 subunit beta Neighboring gene putative lipopolysaccharide kinase InaA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Intercellular junctions between decidual cells in the growing deciduoma of the pseudopregnant rat uterus. Kleinfeld RG, et al. Biol Reprod, 1976 Dec. PMID 999999
    2. Importance of the maintenance pathway in the regulation of the activity of Escherichia coli ribonucleotide reductase. Hristova D, et al. Biochemistry, 2008 Apr 1. PMID 18314964, Free PMC Article
    3. NrdI, a flavodoxin involved in maintenance of the diferric-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase. Cotruvo JA Jr, et al. Proc Natl Acad Sci U S A, 2008 Sep 23. PMID 18799738, Free PMC Article
    4. Primary structure of the Escherichia coli ribonucleoside diphosphate reductase operon. Carlson J, et al. Proc Natl Acad Sci U S A, 1984 Jul. PMID 6087316, Free PMC Article
    5. Intrinsic and extrinsic approaches for detecting genes in a bacterial genome. Borodovsky M, et al. Nucleic Acids Res, 1994 Nov 11. PMID 7984428, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables electron transfer activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within ferredoxin metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2348514..2348768
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416739.1 ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416739.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AL79
      Conserved Domains (1) summary
      PRK10713
      Location:1 → 84
      PRK10713; 2Fe-2S ferredoxin-like protein
    Nucleotide Protein
    Heading Accession and Version

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