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    nudK GDP-mannose hydrolase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947072, updated on 17-Dec-2024

    Summary

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    Official Symbol
    nudK
    Official Full Name
    GDP-mannose hydrolase
    Primary source
    ECOCYC:EG12410
    Locus tag
    b2467
    See related
    ASAP:ABE-0008123
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2462; yffH
    Summary
    Nudix hydrolase. [More information is available at EcoGene: EG12410]. The nudK gene product is a member of the ADP-ribose pyrophosphatase subfamily of the Nudix hydrolases. [More information is available at EcoCyc: EG12410].
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    Genomic context

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    Sequence:
    NC_000913.3 (2582903..2583478, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene transketolase 2 Neighboring gene DUF1176 domain-containing protein YpfG Neighboring gene putative oxidoreductase AegA Neighboring gene sensor histidine kinase NarQ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition. Boto AN, et al. Proteins, 2011 Aug. PMID 21638333, Free PMC Article
    2. Three new Nudix hydrolases from Escherichia coli. Xu W, et al. J Biol Chem, 2006 Aug 11. PMID 16766526
    3. Structural analysis of a set of proteins resulting from a bacterial genomics project. Badger J, et al. Proteins, 2005 Sep 1. PMID 16021622
    4. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables GDP-mannose hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleoside phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribose phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GDP-mannose hydrolase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2582903..2583478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416962.1 GDP-mannose hydrolase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416962.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FVS8, A0A8S7EDV2
      Conserved Domains (1) summary
      PRK15009
      Location:1 → 191
      PRK15009; GDP-mannose pyrophosphatase NudK; Provisional
    Nucleotide Protein
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