U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    truD tRNA pseudouridine(13) synthase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947214, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    truD
    Official Full Name
    tRNA pseudouridine(13) synthase
    Primary source
    ECOCYC:G7422
    Locus tag
    b2745
    See related
    ASAP:ABE-0009011
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2740; ygbO
    Summary
    TruD is responsible for biosynthesis of the pseudouridine13 modification of tRNA(Glu) . [More information is available at EcoCyc: G7422].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (2870255..2871304, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene murein hydrolase activator NlpD Neighboring gene protein-L-isoaspartate O-methyltransferase Neighboring gene broad specificity 5'(3')-nucleotidase and polyphosphatase Neighboring gene 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Neighboring gene 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Neighboring gene cell division protein FtsB

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Expression, purification, crystallization and preliminary diffraction studies of the tRNA pseudouridine synthase TruD from Escherichia coli. Ericsson UB, et al. Acta Crystallogr D Biol Crystallogr, 2004 Apr. PMID 15039583
    2. Thermofluor-based high-throughput stability optimization of proteins for structural studies. Ericsson UB, et al. Anal Biochem, 2006 Oct 15. PMID 16962548
    3. Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold. Kaya Y, et al. J Biol Chem, 2004 Apr 30. PMID 14999002
    4. Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold. Hoang C, et al. RNA, 2004 Jul. PMID 15208439, Free PMC Article
    5. A new gene involved in stationary-phase survival located at 59 minutes on the Escherichia coli chromosome. Li C, et al. J Bacteriol, 1994 Oct. PMID 7928962, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables catalytic activity, acting on RNA IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pseudouridine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA pseudouridine synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tRNA pseudouridine(13) synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within pseudouridine synthesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA pseudouridine synthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tRNA pseudouridine(13) synthase
    NP_417225.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2870255..2871304 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417225.1 tRNA pseudouridine(13) synthase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417225.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7X8N6
      Conserved Domains (1) summary
      PRK00984
      Location:1 → 341
      truD; tRNA pseudouridine synthase D; Reviewed
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.