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    aas fused 2-acylglycerophospho-ethanolamine acyltransferase/acyl-acyl carrier protein synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947315, updated on 3-Dec-2024

    Summary

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    Official Symbol
    aas
    Official Full Name
    fused 2-acylglycerophospho-ethanolamine acyltransferase/acyl-acyl carrier protein synthetase
    Primary source
    ECOCYC:EG11679
    Locus tag
    b2836
    See related
    ASAP:ABE-0009302
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2832
    Summary
    The protein contains bound ACP. [More information is available at EcoCyc: EG11679].
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    Genomic context

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    Sequence:
    NC_000913.3 (2973855..2976014, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF903 domain-containing lipoprotein YgdR Neighboring gene putative NADP(H)-dependent aldo-keto reductase Tas Neighboring gene lysophospholipid transporter Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression and purification of the Escherichia coli inner membrane enzyme acyl-acyl carrier protein synthase in an active form. Shanklin J. Protein Expr Purif, 2000 Apr. PMID 10733890
    2. Turnover of fatty acids in the 1-position of phosphatidylethanolamine in Escherichia coli. Rock CO. J Biol Chem, 1984 May 25. PMID 6373752
    3. 2-Acylglycerolphosphoethanolamine acyltransferase/acyl-acyl carrier protein synthetase is a membrane-associated acyl carrier protein binding protein. Cooper CL, et al. J Biol Chem, 1989 May 5. PMID 2540190
    4. Solubilization, purification, and salt activation of acyl-acyl carrier protein synthetase from Escherichia coli. Rock CO, et al. J Biol Chem, 1979 Aug 10. PMID 378999
    5. Lysophospholipid remodeling mediated by the LplT and Aas protein complex in the bacterial envelope. Niu W, et al. J Biol Chem, 2024 Sep. PMID 39173951, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Lysophospholipid remodeling mediated by the LplT and Aas protein complex in the bacterial envelope.
      Title: Lysophospholipid remodeling mediated by the LplT and Aas protein complex in the bacterial envelope.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity, forming carbon-sulfur bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables long-chain fatty acid [acyl-carrier-protein] ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables long-chain fatty acid [acyl-carrier-protein] ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables long-chain fatty acid-CoA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within fatty acid metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in long-chain fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phospholipid biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fused 2-acylglycerophospho-ethanolamine acyltransferase/acyl-acyl carrier protein synthetase
    NP_417313.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2973855..2976014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417313.1 fused 2-acylglycerophospho-ethanolamine acyltransferase/acyl-acyl carrier protein synthetase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417313.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FXC0
      Conserved Domains (1) summary
      PRK08043
      Location:1 → 718
      PRK08043; bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase
    Nucleotide Protein
    Heading Accession and Version

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