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    ygeH putative transcriptional regulator YgeH [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946265, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ygeH
    Official Full Name
    putative transcriptional regulator YgeH
    Primary source
    ECOCYC:G7472
    Locus tag
    b2852
    See related
    ASAP:ABE-0009368
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2850
    Summary
    This gene is a remnant of the type three secretion system (T3SS) pathogenicity island ETT2. [More information is available at EcoGene: EG13038]. ygeH is located within a remnant of an ETT2 (type III secretion system) pathogenicity island that is fully present in pathogenic strains such as Escherichia coli O157:H7 and at least partially present in most sequenced Escherichia coli and Shigella strains . [More information is available at EcoCyc: G7472].
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    Genomic context

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    Sequence:
    NC_000913.3 (2992094..2993470)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene TPR repeat-containing putative chaperone YgeG Neighboring gene protein YgeI Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HilA-like regulators in Escherichia coli pathotypes: the YgeH protein from the enteroaggregative strain 042. Hüttener M, et al. BMC Microbiol, 2014 Oct 25. PMID 25343852, Free PMC Article
    2. The ETT2 gene cluster, encoding a second type III secretion system from Escherichia coli, is present in the majority of strains but has undergone widespread mutational attrition. Ren CP, et al. J Bacteriol, 2004 Jun. PMID 15150243, Free PMC Article
    3. A degenerate type III secretion system from septicemic Escherichia coli contributes to pathogenesis. Ideses D, et al. J Bacteriol, 2005 Dec. PMID 16291689, Free PMC Article
    4. Visualizing the proteome of Escherichia coli: an efficient and versatile method for labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes. Watt RM, et al. Nucleic Acids Res, 2007. PMID 17272300, Free PMC Article
    5. Phenotypic screening of Escherichia coli K-12 Tn5 insertion libraries, using whole-genome oligonucleotide microarrays. Winterberg KM, et al. Appl Environ Microbiol, 2005 Jan. PMID 15640221, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Escherichia coli 042 YgeH protein is functional and able to replace HilA in Salmonella.[YgeH]
      Title: HilA-like regulators in Escherichia coli pathotypes: the YgeH protein from the enteroaggregative strain 042.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphorelay signal transduction system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative transcriptional regulator YgeH

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2992094..2993470
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417329.1 putative transcriptional regulator YgeH [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417329.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T6QGB6
      Conserved Domains (2) summary
      PRK11906
      Location:1 → 458
      PRK11906; HilA family transcriptional regulator YgeH
      sd00006
      Location:371 → 401
      TPR; TPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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