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    uacT urate:H(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949017, updated on 3-Dec-2024

    Summary

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    Official Symbol
    uacT
    Official Full Name
    urate:H(+) symporter
    Primary source
    ECOCYC:G7507
    Locus tag
    b2888
    See related
    ASAP:ABE-0009478
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2883; ygfU
    Summary
    Related to B. subtilis pbuX. [More information is available at EcoGene: EG13071]. The YgfU protein is an uncharacterised member of the NCS2 family of nucleobase transporters. [More information is available at EcoCyc: G7507].
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    Genomic context

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    Sequence:
    NC_000913.3 (3031367..3032815)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative electron transport protein YgfS Neighboring gene putative oxidoreductase YgfT Neighboring gene uncharacterized protein YqfG Neighboring gene protein YqfH Neighboring gene isopentenyl-diphosphate Delta-isomerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Substrate selectivity of YgfU, a uric acid transporter from Escherichia coli. Papakostas K, et al. J Biol Chem, 2012 May 4. PMID 22437829, Free PMC Article
    2. Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage. Xi H, et al. J Bacteriol, 2000 Oct. PMID 10986234, Free PMC Article
    3. Global analysis of candidate genes important for fitness in a competitive biofilm using DNA-array-based transposon mapping. Junker LM, et al. Microbiology (Reading), 2006 Aug. PMID 16849790
    4. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447
    5. Global topology analysis of the Escherichia coli inner membrane proteome. Daley DO, et al. Science, 2005 May 27. PMID 15919996

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables nucleobase transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables urate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables xanthine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables xanthine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleobase transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within urate transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in xanthine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within xanthine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    urate:H(+) symporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3031367..3032815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417364.2 urate:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417364.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A797HWF0
      Conserved Domains (1) summary
      TIGR03173
      Location:34 → 443
      pbuX; xanthine permease
    Nucleotide Protein
    Heading Accession and Version

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