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    zntR DNA-binding transcriptional activator ZntR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947786, updated on 3-Dec-2024

    Summary

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    Official Symbol
    zntR
    Official Full Name
    DNA-binding transcriptional activator ZntR
    Primary source
    ECOCYC:EG11969
    Locus tag
    b3292
    See related
    ASAP:ABE-0010793
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3279; yhdM
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    Genomic context

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    Sequence:
    NC_000913.3 (3438705..3439130, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene NAD-binding component of Trk potassium transporters Neighboring gene large conductance mechanosensitive channel Neighboring gene alternative ribosome-rescue factor A Neighboring gene DUF1992 domain-containing protein YhdN Neighboring gene 50S ribosomal subunit protein L17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ligand-controlled proteolysis of the Escherichia coli transcriptional regulator ZntR. Pruteanu M, et al. J Bacteriol, 2007 Apr. PMID 17220226, Free PMC Article
    2. The functional analysis of directed amino-acid alterations in ZntR from Escherichia coli. Khan S, et al. Biochem Biophys Res Commun, 2002 Dec 6. PMID 12445820
    3. ZntR-mediated transcription of zntA responds to nanomolar intracellular free zinc. Wang D, et al. J Inorg Biochem, 2012 Jun. PMID 22459916, Free PMC Article
    4. Simulating in vitro transcriptional response of zinc homeostasis system in Escherichia coli. Cui J, et al. BMC Syst Biol, 2008 Oct 24. PMID 18950480, Free PMC Article
    5. DNA distortion mechanism for transcriptional activation by ZntR, a Zn(II)-responsive MerR homologue in Escherichia coli. Outten CE, et al. J Biol Chem, 1999 Dec 31. PMID 10608803

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional activator ZntR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3438705..3439130 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417751.1 DNA-binding transcriptional activator ZntR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417751.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377BX35
      Conserved Domains (1) summary
      PRK09514
      Location:1 → 140
      zntR; Zn(2+)-responsive transcriptional regulator
    Nucleotide Protein
    Heading Accession and Version

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