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    kefG glutathione-regulated potassium-efflux system ancillary protein KefG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947857, updated on 17-Dec-2024

    Summary

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    Official Symbol
    kefG
    Official Full Name
    glutathione-regulated potassium-efflux system ancillary protein KefG
    Primary source
    ECOCYC:G7717
    Locus tag
    b3351
    See related
    ASAP:ABE-0010951
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3339; yheR
    Summary
    KefG is required for KefB activity . [More information is available at EcoCyc: G7717].
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    Genomic context

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    Sequence:
    NC_000913.3 (3480607..3481161, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene FKBP-type peptidyl-prolyl cis-trans isomerase SlyD Neighboring gene DUF2387 domain-containing protein YheV Neighboring gene K(+) : H(+) antiporter KefB Neighboring gene putative ATP-binding protein YheS Neighboring gene putative hydrolase YheT Neighboring gene PF06794 family protein YheU

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Survival during exposure to the electrophilic reagent N-ethylmaleimide in Escherichia coli: role of KefB and KefC potassium channels. Ferguson GP, et al. J Bacteriol, 1997 Feb. PMID 9023177, Free PMC Article
    2. Identification of an ancillary protein, YabF, required for activity of the KefC glutathione-gated potassium efflux system in Escherichia coli. Miller S, et al. J Bacteriol, 2000 Nov. PMID 11053405, Free PMC Article
    3. Three two-component transporters with channel-like properties have monovalent cation/proton antiport activity. Fujisawa M, et al. Proc Natl Acad Sci U S A, 2007 Aug 14. PMID 17679694, Free PMC Article
    4. An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). Reed JL, et al. Genome Biol, 2003. PMID 12952533, Free PMC Article
    5. TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Saier MH Jr, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381841, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables FMN binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables NAD(P)H dehydrogenase (quinone) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables NAD(P)H dehydrogenase (quinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADH:ubiquinone reductase (non-electrogenic) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADPH dehydrogenase (quinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables electron transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of potassium ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of intracellular pH NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of potassium:proton antiporter complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutathione-regulated potassium-efflux system ancillary protein KefG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3480607..3481161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417810.1 glutathione-regulated potassium-efflux system ancillary protein KefG [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417810.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1D7PE49, A0AA35F7N4, A0AAJ3TYU6, A0AAN4AGY2, A0AAX0QI61
      Conserved Domains (1) summary
      PRK04930
      Location:1 → 184
      PRK04930; glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional
    Nucleotide Protein
    Heading Accession and Version

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