U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rbsR DNA-binding transcriptional dual regulator RbsR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948266, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rbsR
    Official Full Name
    DNA-binding transcriptional dual regulator RbsR
    Primary source
    ECOCYC:EG10819
    Locus tag
    b3753
    See related
    ASAP:ABE-0012271
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3747
    Summary
    The transcription factor RbsR, for "Ribose Repressor," is negatively autoregulated and controls the transcription of the operon involved in ribose catabolism and transport . [More information is available at EcoCyc: EG10819].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (3938227..3939219)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ribose ABC transporter periplasmic binding protein Neighboring gene ncRNA Neighboring gene ribokinase Neighboring gene putative transporter HsrA Neighboring gene DNA-binding transcriptional regulator YieP Neighboring gene 16S ribosomal RNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Involvement of the ribose operon repressor RbsR in regulation of purine nucleotide synthesis in Escherichia coli. Shimada T, et al. FEMS Microbiol Lett, 2013 Jul. PMID 23651393
    2. Structural homology between rbs repressor and ribose binding protein implies functional similarity. Mauzy CA, et al. Protein Sci, 1992 Jul. PMID 1304370, Free PMC Article
    3. Structural and functional analyses of the repressor, RbsR, of the ribose operon of Escherichia coli. Mauzy CA, et al. Protein Sci, 1992 Jul. PMID 1304369, Free PMC Article
    4. Computational analysis of the transcriptional regulation of pentose utilization systems in the gamma subdivision of Proteobacteria. Laikova ON, et al. FEMS Microbiol Lett, 2001 Dec 18. PMID 11750821
    5. D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport. Lopilato JE, et al. J Bacteriol, 1984 May. PMID 6327616, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RbsR is a global regulator for switch control between the de novo synthesis of purine nucleotides and its salvage pathway.
      Title: Involvement of the ribose operon repressor RbsR in regulation of purine nucleotide synthesis in Escherichia coli.
    2. N-terminus verified by Edman degradation on mature peptide
      Title: Structural and functional analyses of the repressor, RbsR, of the ribose operon of Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA-binding transcriptional dual regulator RbsR

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3938227..3939219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418209.1 DNA-binding transcriptional dual regulator RbsR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418209.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376CVZ8, A0A895NWY4
      Conserved Domains (1) summary
      PRK10423
      Location:4 → 330
      PRK10423; transcriptional repressor RbsR; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials