U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    osmY periplasmic chaperone OsmY [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948895, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    osmY
    Official Full Name
    periplasmic chaperone OsmY
    Primary source
    ECOCYC:EG11391
    Locus tag
    b4376
    See related
    ASAP:ABE-0014348
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    csi-5; ECK4367
    Summary
    RpoS regulon. [More information is available at EcoGene: EG11391]. Mutation of osmY resulted in increases sensitivity to hyperosmotic stress . [More information is available at EcoCyc: EG11391].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4611396..4612001)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pyrimidine 5'-nucleotidase YjjG Neighboring gene peptide chain release factor RF3 Neighboring gene DUF1328 domain-containing protein YtjA Neighboring gene putative patatin-like phospholipase YjjU Neighboring gene putative metal-dependent hydrolase YjjV

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Chaperone OsmY facilitates the biogenesis of a major family of autotransporters. Yan Z, et al. Mol Microbiol, 2019 Nov. PMID 31369167, Free PMC Article
    2. osmY, a new hyperosmotically inducible gene, encodes a periplasmic protein in Escherichia coli. Yim HH, et al. J Bacteriol, 1992 Jun. PMID 1317380, Free PMC Article
    3. Regulation of envelope protein composition during adaptation to osmotic stress in Escherichia coli. Barron A, et al. J Bacteriol, 1986 Aug. PMID 3015869, Free PMC Article
    4. Complex transcriptional control of the sigma s-dependent stationary-phase-induced and osmotically regulated osmY (csi-5) gene suggests novel roles for Lrp, cyclic AMP (cAMP) receptor protein-cAMP complex, and integration host factor in the stationary-phase response of Escherichia coli. Lange R, et al. J Bacteriol, 1993 Dec. PMID 8253679, Free PMC Article
    5. Molecular characterization of the promoter of osmY, an rpoS-dependent gene. Yim HH, et al. J Bacteriol, 1994 Jan. PMID 8282684, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Structure and Function of the Bacterial Osmotically Inducible Protein Y.
      Title: The Structure and Function of the Bacterial Osmotically Inducible Protein Y.
    2. The results indicate that OsmY is involved in the biogenesis of a major subset of autotransporters, a group of proteins that play key roles in bacterial pathogenesis.
      Title: Chaperone OsmY facilitates the biogenesis of a major family of autotransporters.
    3. A C-terminal tail unique among sigma factors is shown to be required for in vivo recruitment of RNA polymerase to the promoter region prior to osmotic shock.
      Title: Poising of Escherichia coli RNA polymerase and its release from the sigma 38 C-terminal tail for osmY transcription.
    4. N-terminus verified by Edman degradation on mature peptide
      Title: Protein identification with N and C-terminal sequence tags in proteome projects.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chaperone-mediated protein folding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in hyperosmotic response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    periplasmic chaperone OsmY

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4611396..4612001
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418793.1 periplasmic chaperone OsmY [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418793.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5ZI25
      Conserved Domains (1) summary
      PRK10568
      Location:3 → 201
      PRK10568; molecular chaperone OsmY
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.