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    trhP tRNA wobble base hydroxylation protein TrhP [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946609, updated on 3-Dec-2024

    Summary

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    Official Symbol
    trhP
    Official Full Name
    tRNA wobble base hydroxylation protein TrhP
    Primary source
    ECOCYC:G7118
    Locus tag
    b2081
    See related
    ASAP:ABE-0006891
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2077; yegQ
    Summary
    AFMB Structural Genomics target Number 18 (http://afmb.cnrs-mrs.fr/article171.html). ydcP, yegQ, yhbU, and yhbV are paralogs. [More information is available at EcoGene: EG14060].
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    Genomic context

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    Sequence:
    NC_000913.3 (2165668..2167029)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene sensor histidine kinase BaeS Neighboring gene DNA-binding transcriptional activator BaeR Neighboring gene DUF1508 domain-containing protein YegP Neighboring gene ncRNA Neighboring gene prophage P2 late control protein OgrK

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. From the genome sequence to the proteome and back: evaluation of E. coli genome annotation with a 2-D gel-based proteomics approach. Maillet I, et al. Proteomics, 2007 Apr. PMID 17366475
    2. A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map. Itoh T, et al. DNA Res, 1996 Dec 31. PMID 9097040
    3. MEROPS: the peptidase database. Rawlings ND, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381862, Free PMC Article
    4. Dual pathways of tRNA hydroxylation ensure efficient translation by expanding decoding capability. Sakai Y, et al. Nat Commun, 2019 Jun 28. PMID 31253794, Free PMC Article
    5. Identification and Characterization of Genes Required for 5-Hydroxyuridine Synthesis in Bacillus subtilis and Escherichia coli tRNA. Lauhon CT. J Bacteriol, 2019 Oct 15. PMID 31358606, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA modification IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA wobble uridine modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tRNA wobble base hydroxylation protein TrhP

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2165668..2167029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416585.1 tRNA wobble base hydroxylation protein TrhP [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416585.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9QBN0
      Conserved Domains (1) summary
      PRK15452
      Location:1 → 443
      PRK15452; putative protease; Provisional
    Nucleotide Protein
    Heading Accession and Version

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