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    trmH tRNA (Gm18) 2'-O-methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948161, updated on 3-Dec-2024

    Summary

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    Official Symbol
    trmH
    Official Full Name
    tRNA (Gm18) 2'-O-methyltransferase
    Primary source
    ECOCYC:EG10967
    Locus tag
    b3651
    See related
    ASAP:ABE-0011937
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3641; spoU
    Summary
    TrmH is a tRNA 2'-O-methyltransferase that specifically modifies tRNA at position G18 . [More information is available at EcoCyc: EG10967].
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    Genomic context

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    Sequence:
    NC_000913.3 (3824515..3825204)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA polymerase subunit omega Neighboring gene bifunctional (p)ppGpp synthase/hydrolase SpoT Neighboring gene ATP-dependent DNA helicase RecG Neighboring gene glutamate:sodium symporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Physiological analysis of the role of truB in Escherichia coli: a role for tRNA modification in extreme temperature resistance. Kinghorn SM, et al. Microbiology (Reading), 2002 Nov. PMID 12427942
    2. Identification of new RNA modifying enzymes by iterative genome search using known modifying enzymes as probes. Gustafsson C, et al. Nucleic Acids Res, 1996 Oct 1. PMID 8871555, Free PMC Article
    3. Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulence genes in Shigella flexneri. Urbonavicius J, et al. J Bacteriol, 2002 Oct. PMID 12218021, Free PMC Article
    4. Characterization of the spoT gene of Escherichia coli. Sarubbi E, et al. J Biol Chem, 1989 Sep 5. PMID 2549050
    5. Molecular organization and nucleotide sequence of the recG locus of Escherichia coli K-12. Lloyd RG, et al. J Bacteriol, 1991 Nov. PMID 1938888, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (guanine(18)-2'-O)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA guanine ribose methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA guanine ribose methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA guanine ribose methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in tRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA methylation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tRNA (Gm18) 2'-O-methyltransferase
    NP_418108.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3824515..3825204
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418108.1 tRNA (Gm18) 2'-O-methyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418108.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376JQU7, A0A3K0WCF1, A0A5D8M9V8
      Conserved Domains (1) summary
      PRK11081
      Location:1 → 228
      PRK11081; tRNA guanosine-2'-O-methyltransferase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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