U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ppc phosphoenolpyruvate carboxylase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948457, updated on 3-Dec-2024

    Summary

    Official Symbol
    ppc
    Official Full Name
    phosphoenolpyruvate carboxylase
    Primary source
    ECOCYC:EG10756
    Locus tag
    b3956
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    asp; ECK3947; glu
    Summary
    Mutant has reduced growth rate with little acetate excreation, decrease glucose consumption and a decreased carbon dioxide evolution rate. [More information is available at EcoGene: EG10756]. Mutants in the ppc gene have been isolated and studied . [More information is available at EcoCyc: EG10756].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Sequence:
    NC_000913.3 (4150447..4153098, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative PTS enzyme IIB component FrwD Neighboring gene putative DNA-binding transcriptional regulator YijO Neighboring gene phosphoethanolamine transferase EptC Neighboring gene acetylornithine deacetylase Neighboring gene N-acetylglutamylphosphate reductase

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoenolpyruvate carboxylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphoenolpyruvate carboxylase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphoenolpyruvate carboxylase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in carbon fixation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within gluconeogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in oxaloacetate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within oxaloacetate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within protein homotetramerization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    phosphoenolpyruvate carboxylase
    NP_418391.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4150447..4153098 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418391.1 phosphoenolpyruvate carboxylase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418391.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A895NT82
      Conserved Domains (1) summary
      PRK00009
      Location:1883
      PRK00009; phosphoenolpyruvate carboxylase; Reviewed