U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    caiF DNA-binding transcriptional activator CaiF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944795, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    caiF
    Official Full Name
    DNA-binding transcriptional activator CaiF
    Primary source
    ECOCYC:G6088
    Locus tag
    b0034
    See related
    ASAP:ABE-0000125
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0035
    Summary
    A 59 aa ORF yaaV (EG12706) was previously annotated upstream of caiF. yaaV has also been reported as a pseudogene, but the allelic variation, lack of homologs, rare codons, map position and poor RBS indicate it is not a gene and it has been removed. [More information is available at EcoGene: EG13451]. Under anaerobiosis and in the presence of "carnitine," CaiF activates the transcription of genes involved in carnitine metabolism . [More information is available at EcoCyc: G6088].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (34300..34695)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene carbamoyl-phosphate synthetase small subunit Neighboring gene carbamoyl-phosphate synthetase large subunit Neighboring gene putative transferase CaiE Neighboring gene crotonobetainyl-CoA hydratase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Positive co-regulation of the Escherichia coli carnitine pathway cai and fix operons by CRP and the CaiF activator. Buchet A, et al. Mol Microbiol, 1999 Nov. PMID 10564497
    2. Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region. Buchet A, et al. J Bacteriol, 1998 May. PMID 9573142, Free PMC Article
    3. Identification and characterization of the caiF gene encoding a potential transcriptional activator of carnitine metabolism in Escherichia coli. Eichler K, et al. J Bacteriol, 1996 Mar. PMID 8631699, Free PMC Article
    4. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within carnitine metabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA-binding transcriptional activator CaiF

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      34300..34695
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414576.4 DNA-binding transcriptional activator CaiF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414576.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5YAV5
      Conserved Domains (1) summary
      PRK11476
      Location:19 → 131
      PRK11476; carnitine metabolism transcriptional regulator CaiF
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.