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    fdnH formate dehydrogenase N subunit beta [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948794, updated on 3-Dec-2024

    Summary

    Official Symbol
    fdnH
    Official Full Name
    formate dehydrogenase N subunit beta
    Primary source
    ECOCYC:EG11228
    Locus tag
    b1475
    See related
    ASAP:ABE-0004919
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1469
    Summary
    FdnH is co-exported bound to Tat substrate FdnG. [More information is available at EcoGene: EG11228]. FdnH contains four [4Fe-4S] clusters and one C-terminal transmembrane helix . [More information is available at EcoCyc: EG11228].
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    Genomic context

    Sequence:
    NC_000913.3 (1550461..1551345)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene amino acid exporter YddG Neighboring gene formate dehydrogenase N subunit alpha Neighboring gene formate dehydrogenase N subunit gamma Neighboring gene DNA-binding transcriptional regulator YddM Neighboring gene ethanol dehydrogenase/alcohol dehydrogenase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables electron transfer activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables formate dehydrogenase (quinone) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in anaerobic electron transport chain NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within anaerobic respiration IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular respiration IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within formate oxidation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in formate oxidation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in formate oxidation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in heme oxidation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of formate dehydrogenase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of formate dehydrogenase complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    located_in membrane HDA PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    formate dehydrogenase N subunit beta
    NP_415992.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1550461..1551345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415992.1 formate dehydrogenase N subunit beta [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415992.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2H4U051, A0A6C9QFE0
      Conserved Domains (1) summary
      TIGR01582
      Location:7290
      FDH-beta; formate dehydrogenase, beta subunit, Fe-S containing