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    rplT 50S ribosomal subunit protein L20 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945152, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rplT
    Official Full Name
    50S ribosomal subunit protein L20
    Primary source
    ECOCYC:EG10881
    Locus tag
    b1716
    See related
    ASAP:ABE-0005729
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1714; pdzA
    Summary
    The L20 protein is a component of the 50S subunit of the ribosome and autoregulates its own expression and that of L35 at the posttranscriptional level. [More information is available at EcoCyc: EG10881].
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    Genomic context

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    Sequence:
    NC_000913.3 (1799393..1799749, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene phenylalanine--tRNA ligase subunit alpha Neighboring gene pheST-ihfA operon leader peptide Neighboring gene 50S ribosomal subunit protein L35 Neighboring gene translation initiation factor IF-3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Translational coupling in the Escherichia coli operon encoding translation initiation factor IF3 and ribosomal proteins L20 and L35. Chiaruttini C, et al. Biochimie, 1996. PMID 8955899
    2. The primary structure of protein L20 from the large subunit of the Escherichia coli ribosome. Wittmann-Liebold B, et al. FEBS Lett, 1979 Jul 1. PMID 381019
    3. Binding of aminoacyl-tRNA to reconstituted subparticles of Escherichia coli large ribosomal subunits. Kazemie M. Eur J Biochem, 1976 Aug 16. PMID 786630
    4. Protein L20 from the large subunit of Escherichia coli ribosomes is an assembly protein. Nowotny V, et al. J Mol Biol, 1980 Mar 15. PMID 7021848
    5. A long-range RNA-RNA interaction forms a pseudoknot required for translational control of the IF3-L35-L20 ribosomal protein operon in Escherichia coli. Chiaruttini C, et al. EMBO J, 1996 Aug 15. PMID 8861967, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: A method for the chemical generation of N-terminal peptide sequence tags for rapid protein identification.
    2. Only one molecule of L20 protein binds to the L20 mRNA despite the presence of two potential binding sites.
      Title: Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites.
    3. findings demonstrate double molecular mimicry: binding of ribosomal protein L20 to its two sites in mRNA is similar to its binding to 23S rRNA
      Title: Double molecular mimicry in Escherichia coli: binding of ribosomal protein L20 to its two sites in mRNA is similar to its binding to 23S rRNA.
    4. N-terminal tail of L20 is important for ribosome assembly in vivo
      Title: The N-terminal extension of Escherichia coli ribosomal protein L20 is important for ribosome assembly, but dispensable for translational feedback control.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables large ribosomal subunit rRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA regulatory element binding translation repressor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ribosomal large subunit assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ribosomal large subunit assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ribosomal large subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    50S ribosomal subunit protein L20

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1799393..1799749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416231.1 50S ribosomal subunit protein L20 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416231.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      W1X3C7
      Conserved Domains (1) summary
      PRK05185
      Location:2 → 115
      rplT; 50S ribosomal protein L20; Provisional
    Nucleotide Protein
    Heading Accession and Version

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