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    recB exodeoxyribonuclease V subunit RecB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947286, updated on 3-Dec-2024

    Summary

    Official Symbol
    recB
    Official Full Name
    exodeoxyribonuclease V subunit RecB
    Primary source
    ECOCYC:EG10824
    Locus tag
    b2820
    See related
    ASAP:ABE-0009249
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2816; ior; rorA
    Summary
    RecBCD is a bipolar helicase. [More information is available at EcoGene: EG10824]. RecB, RecC, and RecD make up a helicase/nuclease complex that is essential for both homologous recombination during the course of transduction and conjugation as well as in repair of double-strand breaks in Escherichia coli . [More information is available at EcoCyc: EG10824].
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    Genomic context

    Sequence:
    NC_000913.3 (2952461..2956003, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene N-acetylmuramoyl-L-alanine amidase C Neighboring gene N-acetylglutamate synthase Neighboring gene exodeoxyribonuclease V subunit RecD Neighboring gene protease 3 Neighboring gene exodeoxyribonuclease V subunit RecC Neighboring gene prepilin-type N-terminal cleavage/methylation domain-containing protein PpdC Neighboring gene DUF2509 domain-containing protein YgdB

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 3'-5' DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables 3'-5' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent H2AZ histone chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent H3-H4 histone complex chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent activity, acting on DNA IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA clamp loader activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA endonuclease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA helicase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA translocase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables chromatin extrusion motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables cohesin loader activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables exodeoxyribonuclease V activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables exodeoxyribonuclease V activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA recombination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within DNA recombination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin looping IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in clearance of foreign intracellular DNA IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within double-strand break repair via homologous recombination TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in recombinational repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in recombinational repair IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within response to radiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of exodeoxyribonuclease V complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of exodeoxyribonuclease V complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of exodeoxyribonuclease V complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    exodeoxyribonuclease V subunit RecB
    NP_417297.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2952461..2956003 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417297.1 exodeoxyribonuclease V subunit RecB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417297.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6M9X2W8
      Conserved Domains (1) summary
      PRK10876
      Location:11180
      recB; exonuclease V subunit beta; Provisional