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    nirD nitrite reductase (NADH) small subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947881, updated on 3-Dec-2024

    Summary

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    Official Symbol
    nirD
    Official Full Name
    nitrite reductase (NADH) small subunit
    Primary source
    ECOCYC:EG10655
    Locus tag
    b3366
    See related
    ASAP:ABE-0011005
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3354
    Summary
    The nirD gene encodes the small subunit of the nitrite reductase. [More information is available at EcoCyc: EG10655].
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    Genomic context

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    Sequence:
    NC_000913.3 (3496551..3496877)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase A Neighboring gene putative transporter TsgA Neighboring gene nitrite reductase (NADH) large subunit Neighboring gene nitrite transporter NirC Neighboring gene siroheme synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Electron-spin-resonance studies of the NADH-dependent nitrite reductase from Escherichia coli K12. Cammack R, et al. Biochem J, 1982 Nov 1. PMID 6297458, Free PMC Article
    2. Purification and properties of nitrite reductase from Escherichia coli K12. Coleman KJ, et al. Biochem J, 1978 Nov 1. PMID 217342, Free PMC Article
    3. The steady-state kinetics of the NADH-dependent nitrite reductase from Escherichia coli K 12. Nitrite and hydroxylamine reduction. Jackson RH, et al. Biochem J, 1981 Oct 1. PMID 6279095, Free PMC Article
    4. Clustering as a Means To Control Nitrate Respiration Efficiency and Toxicity in Escherichia coli. Bulot S, et al. mBio, 2019 Oct 22. PMID 31641084, Free PMC Article
    5. Suppression of FNR-dependent transcription activation at the Escherichia coli nir promoter by Fis, IHF and H-NS: modulation of transcription initiation by a complex nucleo-protein assembly. Browning DF, et al. Mol Microbiol, 2000 Sep. PMID 10972841

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NirD curtails the stringent response by inhibiting RelA activity in Escherichia coli.
      Title: NirD curtails the stringent response by inhibiting RelA activity in Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to nitrite reductase NADH activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nitrite reductase NADH activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to nitrite reductase NADH activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nitrate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nitrite reductase complex [NAD(P)H] IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nitrite reductase complex [NAD(P)H] IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nitrite reductase (NADH) small subunit
    NP_417825.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3496551..3496877
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417825.1 nitrite reductase (NADH) small subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417825.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S0FE84, A0A8S7CT45
      Conserved Domains (1) summary
      PRK09511
      Location:1 → 108
      nirD; nitrite reductase small subunit NirD
    Nucleotide Protein
    Heading Accession and Version

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