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    wcaI colanic acid biosynthesis fucosyltransferase WcaI [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946588, updated on 17-Dec-2024

    Summary

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    Official Symbol
    wcaI
    Official Full Name
    colanic acid biosynthesis fucosyltransferase WcaI
    Primary source
    ECOCYC:EG11790
    Locus tag
    b2050
    See related
    ASAP:ABE-0006794
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2044; yefD
    Summary
    WcaI is believed to be a glycosyl transferase involved in colanic acid synthesis based on sequence similarity and its presence in a putative colanic acid synthesis operon . [More information is available at EcoCyc: EG11790].
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    Genomic context

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    Sequence:
    NC_000913.3 (2124523..2125746, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphomannomutase Neighboring gene mannose-1-phosphate guanylyltransferase Neighboring gene GDP-mannose mannosyl hydrolase Neighboring gene GDP-L-fucose synthase Neighboring gene GDP-mannose 4,6-dehydratase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evidence for effect of random genetic drift on G+C content after lateral transfer of fucose pathway genes to Escherichia coli K-12. Aoyama K, et al. Mol Biol Evol, 1994 Nov. PMID 7815923
    2. Biosynthesis and assembly of capsular polysaccharides in Escherichia coli. Whitfield C. Annu Rev Biochem, 2006. PMID 16756484
    3. Development of a biofilm production-deficient Escherichia coli strain as a host for biotechnological applications. Sung BH, et al. Appl Environ Microbiol, 2006 May. PMID 16672475, Free PMC Article
    4. Genome-wide analyses revealing a signaling network of the RcsC-YojN-RcsB phosphorelay system in Escherichia coli. Hagiwara D, et al. J Bacteriol, 2003 Oct. PMID 13129944, Free PMC Article
    5. Identification of the Functional Roles of Six Key Proteins in the Biosynthesis of Enterobacteriaceae Colanic Acid. Scott PM, et al. Biochemistry, 2019 Apr 2. PMID 30821147, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables alpha-(1->3)-fucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in colanic acid biosynthetic process IGC
    Inferred from Genomic Context
    more info
    		 PubMed 
    involved_in lipopolysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in slime layer polysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    colanic acid biosynthesis fucosyltransferase WcaI

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2124523..2125746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416554.1 colanic acid biosynthesis fucosyltransferase WcaI [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416554.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3K0W8U4
      Conserved Domains (1) summary
      TIGR04007
      Location:1 → 407
      wcaI; colanic acid biosynthesis glycosyl transferase WcaI
    Nucleotide Protein
    Heading Accession and Version

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