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    ilvH acetolactate synthase/acetohydroxybutanoate synthase, regulatory subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947267, updated on 3-Dec-2024

    Summary

    Official Symbol
    ilvH
    Official Full Name
    acetolactate synthase/acetohydroxybutanoate synthase, regulatory subunit
    Primary source
    ECOCYC:EG10499
    Locus tag
    b0078
    See related
    ASAP:ABE-0000294
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    brnP; ECK0080
    Summary
    IlvH is the regulatory (small) subunit of acetolactate synthase III; it confers sensitivity to inhibition by valine and is required for full catalytic activity of acetolactate synthase III holoenzyme . [More information is available at EcoCyc: EG10499].
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    Genomic context

    Sequence:
    NC_000913.3 (87357..87848)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YabR Neighboring gene acetolactate synthase/acetohydroxybutanoate synthase, catalytic subunit Neighboring gene DNA-binding transcriptional dual regulator Cra Neighboring gene DNA-binding transcriptional repressor MraZ

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables acetolactate synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables acetolactate synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables acetolactate synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acetolactate synthase regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of acetolactate synthase complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    acetolactate synthase/acetohydroxybutanoate synthase, regulatory subunit
    NP_414620.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      87357..87848
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414620.1 acetolactate synthase/acetohydroxybutanoate synthase, regulatory subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414620.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7T9A2
      Conserved Domains (1) summary
      PRK11895
      Location:1162
      ilvH; acetolactate synthase 3 regulatory subunit; Reviewed