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    brnQ branched chain amino acid transporter BrnQ [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945042, updated on 3-Dec-2024

    Summary

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    Official Symbol
    brnQ
    Official Full Name
    branched chain amino acid transporter BrnQ
    Primary source
    ECOCYC:EG12168
    Locus tag
    b0401
    See related
    ASAP:ABE-0001394
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0395; hrbA
    Summary
    BrnQ is a probable branched chain amino acid transporter. [More information is available at EcoCyc: EG12168].
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    Genomic context

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    Sequence:
    NC_000913.3 (419591..420910)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator PhoB Neighboring gene sensor histidine kinase PhoR Neighboring gene putative transporter ProY Neighboring gene maltodextrin glucosidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Escherichia coli K-12 mutants altered in the transport of branched-chain amino acids. Guardiola J, et al. J Bacteriol, 1971 Dec. PMID 4945181, Free PMC Article
    2. Mutations affecting the different transport systems for isoleucine, leucine, and valine in Escherichia coli K-12. Guardiola J, et al. J Bacteriol, 1974 Feb. PMID 4590465, Free PMC Article
    3. Cloning and nucleotide sequence of the brnQ gene, the structural gene for a membrane-associated component of the LIV-II transport system for branched-chain amino acids in Salmonella typhimurium. Ohnishi K, et al. Jpn J Genet, 1988 Aug. PMID 3078876
    4. Genetic and biochemical studies of transport systems for branched-chain amino acids in Escherichia coli. Yamato I, et al. J Bacteriol, 1979 Apr. PMID 374366, Free PMC Article
    5. Genetic separation of high- and low-affinity transport systems for branched-chain amino acids in Escherichia coli K-12. Anderson JJ, et al. J Bacteriol, 1978 Oct. PMID 361686, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-isoleucine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-isoleucine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables L-leucine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-leucine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables L-valine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-valine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables branched-chain amino acid transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in L-leucine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within L-leucine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in L-valine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in branched-chain amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within branched-chain amino acid transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in isoleucine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within isoleucine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in valine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within valine transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    branched chain amino acid transporter BrnQ

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      419591..420910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414935.1 branched chain amino acid transporter BrnQ [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414935.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9API1
      Conserved Domains (1) summary
      PRK15433
      Location:1 → 439
      PRK15433; branched-chain amino acid transporter carrier protein BrnQ
    Nucleotide Protein
    Heading Accession and Version

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