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    ldcA murein tetrapeptide carboxypeptidase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945756, updated on 17-Dec-2024

    Summary

    Official Symbol
    ldcA
    Official Full Name
    murein tetrapeptide carboxypeptidase
    Primary source
    ECOCYC:G6621
    Locus tag
    b1192
    See related
    ASAP:ABE-0004002
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1180; ycgQ
    Summary
    LdcA mutants can lyse in stationary phase (Templin, 1999; Herve, 2007). [More information is available at EcoGene: EG13898]. LdcA is an L,D-carboxypeptidase that has an essential function in murein (peptidoglycan) recycling/turnover . [More information is available at EcoCyc: G6621].
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    Genomic context

    Sequence:
    NC_000913.3 (1242166..1243080, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene alanine racemase 2 Neighboring gene protein YmgM Neighboring gene putative K(+):H(+) antiporter Neighboring gene lytic murein transglycosylase E Neighboring gene flagellar brake protein YcgR

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidoglycan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidoglycan turnover IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in peptidoglycan turnover IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in peptidoglycan turnover IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidoglycan turnover IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    murein tetrapeptide carboxypeptidase
    NP_415710.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1242166..1243080 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415710.1 murein tetrapeptide carboxypeptidase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415710.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6D0I975
      Conserved Domains (1) summary
      PRK11253
      Location:1304
      ldcA; L,D-carboxypeptidase A; Provisional