U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    trpE anthranilate synthase subunit TrpE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945846, updated on 3-Dec-2024

    Summary

    Official Symbol
    trpE
    Official Full Name
    anthranilate synthase subunit TrpE
    Primary source
    ECOCYC:EG11028
    Locus tag
    b1264
    See related
    ASAP:ABE-0004244
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    anth; ECK1258; tryD; tryp-4
    Summary
    Induced during biofilm formation. [More information is available at EcoGene: EG11028]. Anthranilate synthase (TrpDE) catalyzes the first step in the pathway of tryptophan biosynthesis, and is subject to feedback regulation by the end product of the pathway. [More information is available at EcoCyc: EG11028].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Sequence:
    NC_000913.3 (1321384..1322946, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase Neighboring gene anthranilate synthase subunit TrpD Neighboring gene trp operon leader peptide Neighboring gene RNase AM Neighboring gene putative RNA-binding protein YciO

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables anthranilate synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables anthranilate synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tryptophan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within tryptophan biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in tryptophan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within tryptophan biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in tryptophan biosynthetic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of anthranilate synthase complex NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    anthranilate synthase subunit TrpE
    NP_415780.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1321384..1322946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415780.1 anthranilate synthase subunit TrpE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415780.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376K0Q3, A0AAN5UHE4
      Conserved Domains (1) summary
      PRK13564
      Location:1520
      PRK13564; anthranilate synthase component 1