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    mcbR DNA-binding transcriptional dual regulator McbR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946014, updated on 3-Dec-2024

    Summary

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    Official Symbol
    mcbR
    Official Full Name
    DNA-binding transcriptional dual regulator McbR
    Primary source
    ECOCYC:G6761
    Locus tag
    b1450
    See related
    ASAP:ABE-0004837
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1444; yncC
    Summary
    Salmonella ortholog regulated by RpoS. [More information is available at EcoGene: EG13773]. The yncC gene of Salmonella enterica serovar Typhimurium shows regulation that is RpoS dependent and growth phase dependent . [More information is available at EcoCyc: G6761].
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    Genomic context

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    Sequence:
    NC_000913.3 (1520262..1520927)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative inner membrane protein YdcZ Neighboring gene L-amino acid N-acyltransferase Neighboring gene NADPH-dependent curcumin/dihydrocurcumin reductase Neighboring gene putative TonB-dependent outer membrane receptor Neighboring gene PQQ-like domain-containing protein YncE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chapter 1: Variation in form and function the helix-turn-helix regulators of the GntR superfamily. Hoskisson PA, et al. Adv Appl Microbiol, 2009. PMID 19729089
    2. The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli. Xu Y, et al. J Biol Chem, 2001 May 18. PMID 11279025
    3. Identification of RpoS (sigma(S))-regulated genes in Salmonella enterica serovar typhimurium. Ibanez-Ruiz M, et al. J Bacteriol, 2000 Oct. PMID 11004173, Free PMC Article
    4. Low molecular weight proteins: a challenge for post-genomic research. Rudd KE, et al. Electrophoresis, 1998 Apr. PMID 9588799
    5. DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli. DeLisa MP, et al. J Bacteriol, 2001 Sep. PMID 11514505, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. YncC inhibits colanic acid overproduction and thereby inhibits mucoidy by repressing expression of periplasmic protein YbiM.
      Title: Escherichia coli transcription factor YncC (McbR) regulates colanic acid and biofilm formation by repressing expression of periplasmic protein YbiM (McbA).
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional dual regulator McbR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1520262..1520927
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415967.2 DNA-binding transcriptional dual regulator McbR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415967.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377E4S0
      Conserved Domains (1) summary
      PRK11414
      Location:1 → 221
      PRK11414; GntR family transcriptional regulator
    Nucleotide Protein
    Heading Accession and Version

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