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    tnaB tryptophan:H(+) symporter TnaB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948220, updated on 3-Dec-2024

    Summary

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    Official Symbol
    tnaB
    Official Full Name
    tryptophan:H(+) symporter TnaB
    Primary source
    ECOCYC:EG11006
    Locus tag
    b3709
    See related
    ASAP:ABE-0012135
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3702; tnaP; trpP
    Summary
    HAAAP family. [More information is available at EcoGene: EG11006]. TnaB is one of three known transporters for tryptophan in Escherichia coli, the others being Mtr and AroP. [More information is available at EcoCyc: EG11006].
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    Genomic context

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    Sequence:
    NC_000913.3 (3890236..3891483)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tnaAB operon leader peptide Neighboring gene tryptophanase Neighboring gene efflux pump MdtL Neighboring gene DNA-binding transcriptional dual regulator YidZ Neighboring gene putative phosphopantetheinyl transferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Membrane transport. Oxender DL. Annu Rev Biochem, 1972. PMID 4570962
    2. A copy of insertion element IS5 is present within tnaB in the Kohara library of Escherichia coli W3110. Kamath AV, et al. J Bacteriol, 1994 Mar. PMID 8113202, Free PMC Article
    3. Physiological studies of tryptophan transport and tryptophanase operon induction in Escherichia coli. Yanofsky C, et al. J Bacteriol, 1991 Oct. PMID 1917834, Free PMC Article
    4. Evidence for transcription antitermination control of tryptophanase operon expression in Escherichia coli K-12. Stewart V, et al. J Bacteriol, 1985 Nov. PMID 3902796, Free PMC Article
    5. Nucleotide sequence of the structural gene for tryptophanase of Escherichia coli K-12. Deeley MC, et al. J Bacteriol, 1981 Sep. PMID 6268608, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables aromatic amino acid transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within amino acid transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in aromatic amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tryptophan catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tryptophan:H(+) symporter TnaB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3890236..3891483
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418165.1 tryptophan:H(+) symporter TnaB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418165.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5Z985, A0A8T6BSR0
      Conserved Domains (1) summary
      PRK09664
      Location:1 → 415
      PRK09664; low affinity tryptophan permease TnaB
    Nucleotide Protein
    Heading Accession and Version

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