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    ulaE L-ribulose-5-phosphate 3-epimerase UlaE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948712, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ulaE
    Official Full Name
    L-ribulose-5-phosphate 3-epimerase UlaE
    Primary source
    ECOCYC:G7859
    Locus tag
    b4197
    See related
    ASAP:ABE-0013732
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4193; sgaU; yjfW
    Summary
    The ula divergon is comprised of the two divergent ulaGR and ulaABCDEF operons. [More information is available at EcoGene: EG12497]. L-xylulose 5-phosphate 3-epimerase is an enzyme in the pathway of anaerobic L-ascorbate degradation. [More information is available at EcoCyc: G7859].
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    Genomic context

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    Sequence:
    NC_000913.3 (4422846..4423700)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-ascorbate specific PTS enzyme IIA component Neighboring gene 3-keto-L-gulonate-6-phosphate decarboxylase UlaD Neighboring gene L-ribulose-5-phosphate 4-epimerase UlaF Neighboring gene DUF1471 domain-containing protein YjfY Neighboring gene 30S ribosomal subunit protein S6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of L-xylulose-5-Phosphate 3-epimerase (UlaE) from the anaerobic L-ascorbate utilization pathway of Escherichia coli: identification of a novel phosphate binding motif within a TIM barrel fold. Shi R, et al. J Bacteriol, 2008 Dec. PMID 18849419, Free PMC Article
    2. Aerobic L-ascorbate metabolism and associated oxidative stress in Escherichia coli. Campos E, et al. Microbiology (Reading), 2007 Oct. PMID 17906139
    3. The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli. Campos E, et al. J Bacteriol, 2002 Nov. PMID 12374842, Free PMC Article
    4. The ascorbate transporter of Escherichia coli. Zhang Z, et al. J Bacteriol, 2003 Apr. PMID 12644495, Free PMC Article
    5. Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli. Campos E, et al. J Bacteriol, 2004 Mar. PMID 14996803, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables L-ribulose-5-phosphate 3-epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-ribulose-5-phosphate 3-epimerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-ribulose-5-phosphate 3-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables intramolecular oxidoreductase activity, interconverting aldoses and ketoses IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-ascorbic acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in L-ascorbic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within L-ascorbic acid metabolic process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    L-ribulose-5-phosphate 3-epimerase UlaE
    NP_418618.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4422846..4423700
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418618.1 L-ribulose-5-phosphate 3-epimerase UlaE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418618.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7JQQ1
      Conserved Domains (1) summary
      PRK13209
      Location:1 → 281
      PRK13209; L-ribulose-5-phosphate 3-epimerase
    Nucleotide Protein
    Heading Accession and Version

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