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    chpS ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948739, updated on 17-Dec-2024

    Summary

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    Official Symbol
    chpS
    Official Full Name
    ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system
    Primary source
    ECOCYC:EG11250
    Locus tag
    b4224
    See related
    ASAP:ABE-0013820
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    chpBI; ECK4220; yjfB
    Summary
    ChpS is the antitoxin component of the ChpB-ChpS toxin-antitoxin system. [More information is available at EcoCyc: EG11250].
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    Genomic context

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    Sequence:
    NC_000913.3 (4448447..4448698)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene translocation and assembly module subunit TamA Neighboring gene translocation and assembly module subunit TamB Neighboring gene gamma-glutamylamine cyclotransferase family protein YtfP Neighboring gene endoribonuclease toxin ChpB Neighboring gene inorganic pyrophosphatase Neighboring gene galactofuranose ABC transporter periplasmic binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of ChpBK, an mRNA interferase from Escherichia coli. Zhang Y, et al. J Biol Chem, 2005 Jul 15. PMID 15901733
    2. Functional interactions between chpB and parD, two homologous conditional killer systems found in the Escherichia coli chromosome and in plasmid R1. Santos Sierra S, et al. FEMS Microbiol Lett, 1998 Nov 1. PMID 9812362
    3. Mapping and disruption of the chpB locus in Escherichia coli. Masuda Y, et al. J Bacteriol, 1994 Sep. PMID 8083180, Free PMC Article
    4. Structural analysis of the ileR locus of Escherichia coli K12. Weiss DL, et al. J Biol Chem, 1986 Jul 25. PMID 3525538
    5. Toxin-antitoxin modules may regulate synthesis of macromolecules during nutritional stress. Gerdes K. J Bacteriol, 2000 Feb. PMID 10633087, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables toxin sequestering activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of growth NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in single-species biofilm formation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of toxin-antitoxin complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4448447..4448698
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418645.2 ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418645.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A192CH25, A0AAN4ADS0
      Conserved Domains (1) summary
      PRK11347
      Location:1 → 83
      PRK11347; antitoxin ChpS; Provisional
    Nucleotide Protein
    Heading Accession and Version

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