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    LRP12 LDL receptor related protein 12 [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 102116571, updated on 12-Jun-2024

    Summary

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    Gene symbol
    LRP12
    Gene description
    LDL receptor related protein 12
    See related
    Ensembl:ENSMFAG00000004646
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    LRP-12
    Orthologs
    human mouse all
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    Genomic context

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    See LRP12 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 8 NC_088382.1 (114107171..114199042, complement)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 8 NC_052262.1 (102171510..102263305, complement)

    Chromosome 8 - NC_088382.1Genomic Context describing neighboring genes Neighboring gene dendrocyte expressed seven transmembrane protein Neighboring gene dihydropyrimidinase Neighboring gene uncharacterized LOC135964795 Neighboring gene uncharacterized LOC123575251

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    low-density lipoprotein receptor-related protein 12
    Names
    Low-density lipoprotein receptor-related protein 12
    low density lipoprotein receptor-related protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088382.1 Reference T2T-MFA8v1.0

      Range
      114107171..114199042 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005563904.4 → XP_005563961.1  low-density lipoprotein receptor-related protein 12 isoform X2

      See identical proteins and their annotated locations for XP_005563961.1

      UniProtKB/TrEMBL
      A0A2K5UC80
      Related
      ENSMFAP00000009967.1
      Conserved Domains (2) summary
      cd00041
      Location:28 → 139
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:432 → 466
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

    2. XM_005563903.4 → XP_005563960.1  low-density lipoprotein receptor-related protein 12 isoform X1

      See identical proteins and their annotated locations for XP_005563960.1

      UniProtKB/TrEMBL
      A0A2K5UC79
      Related
      ENSMFAP00000009963.1
      Conserved Domains (2) summary
      cd00041
      Location:47 → 158
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:451 → 485
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BE74.2 GenPept UniProtKB/Swiss-Prot:Q9BE74

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