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    GABRB2 gamma-aminobutyric acid type A receptor subunit beta2 [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 102136509, updated on 12-Jun-2024

    Summary

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    Gene symbol
    GABRB2
    Gene description
    gamma-aminobutyric acid type A receptor subunit beta2
    See related
    Ensembl:ENSMFAG00000033709
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GABRB2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 6 NC_088380.1 (168056426..168320386, complement)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 6 NC_052260.1 (156414219..156677746, complement)

    Chromosome 6 - NC_088380.1Genomic Context describing neighboring genes Neighboring gene ATPase phospholipid transporting 10B (putative) Neighboring gene small ribosomal subunit protein eS8 Neighboring gene uncharacterized LOC135971527 Neighboring gene large ribosomal subunit protein eL29-like Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GABA-A receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables extracellular ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables neurotransmitter receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of GABA-A receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma-aminobutyric acid receptor subunit beta-2
    Names
    GABA-A beta 2 subunit
    gamma-aminobutyric acid type A receptor beta2 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088380.1 Reference T2T-MFA8v1.0

      Range
      168056426..168320386 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005558446.4 → XP_005558503.1  gamma-aminobutyric acid receptor subunit beta-2 isoform X2

      See identical proteins and their annotated locations for XP_005558503.1

      UniProtKB/TrEMBL
      A0A2K5X1S8
      Related
      ENSMFAP00000043226.1
      Conserved Domains (1) summary
      TIGR00860
      Location:9 → 472
      LIC; Cation transporter family protein

    2. XM_005558444.4 → XP_005558501.1  gamma-aminobutyric acid receptor subunit beta-2 isoform X1

      See identical proteins and their annotated locations for XP_005558501.1

      UniProtKB/TrEMBL
      A0A2K5X1U8, A0A8J8YKT6, G7P6T5
      Conserved Domains (1) summary
      TIGR00860
      Location:9 → 510
      LIC; Cation transporter family protein
    Nucleotide Protein
    Heading Accession and Version

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