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    Malsu1 mitochondrial assembly of ribosomal large subunit 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297082, updated on 27-Nov-2024

    Summary

    Official Symbol
    Malsu1provided by RGD
    Official Full Name
    mitochondrial assembly of ribosomal large subunit 1provided by RGD
    Primary source
    RGD:1306936
    See related
    AllianceGenome:RGD:1306936
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306936
    Summary
    Predicted to enable mitochondrial large ribosomal subunit binding activity. Predicted to be involved in negative regulation of mitochondrial translation; negative regulation of ribosome biogenesis; and ribosomal large subunit biogenesis. Predicted to be located in cytosol. Predicted to be active in mitochondrion. Orthologous to human MALSU1 (mitochondrial assembly of ribosomal large subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 145.5), Heart (RPKM 142.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Malsu1 in Genome Data Viewer
    Location:
    4q24
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (79381963..79390786)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (78051090..78059913)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (78735279..78744102)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102546557 Neighboring gene glycoprotein nmb Neighboring gene insulin-like growth factor 2 mRNA binding protein 3 Neighboring gene transformer 2 alpha

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mitochondrial large ribosomal subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribosomal large subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of mitochondrial translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of ribosome biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal large subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitochondrial assembly of ribosomal large subunit protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106593.1NP_001100063.1  mitochondrial assembly of ribosomal large subunit protein 1

      See identical proteins and their annotated locations for NP_001100063.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474011
      UniProtKB/TrEMBL
      A6K0K3, D3ZZ37
      Conserved Domains (1) summary
      pfam02410
      Location:90189
      RsfS; Ribosomal silencing factor during starvation

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      79381963..79390786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)