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    Kctd13 potassium channel tetramerization domain containing 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293497, updated on 9-Dec-2024

    Summary

    Official Symbol
    Kctd13provided by RGD
    Official Full Name
    potassium channel tetramerization domain containing 13provided by RGD
    Primary source
    RGD:735189
    See related
    EnsemblRapid:ENSRNOG00000020010 AllianceGenome:RGD:735189
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables protein domain specific binding activity. Involved in positive regulation of DNA replication. Predicted to be located in nuclear body. Predicted to be part of Cul3-RING ubiquitin ligase complex. Orthologous to human KCTD13 (potassium channel tetramerization domain containing 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 86.4), Testes (RPKM 38.5) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Kctd13 in Genome Data Viewer
    Location:
    1q37
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (190965073..190983381)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (181534534..181552843)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (198360627..198378935)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene TAO kinase 2 Neighboring gene transmembrane protein 219 Neighboring gene uncharacterized LOC108349643 Neighboring gene aspartate beta-hydroxylase domain containing 1 Neighboring gene seizure related 6 homolog like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein domain specific binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Cul3-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1
    Names
    BTB/POZ domain-containing protein KCTD13
    PDIP1
    potassium channel tetramerisation domain containing 13

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198736.1NP_942031.1  BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

      See identical proteins and their annotated locations for NP_942031.1

      Status: PROVISIONAL

      Source sequence(s)
      AY305029
      UniProtKB/TrEMBL
      A6I9J0, F7F8A0, Q7TQ24
      Related
      ENSRNOP00000027129.3, ENSRNOT00000027129.6
      Conserved Domains (1) summary
      cd18400
      Location:40142
      BTB_POZ_KCTD13_BACURD1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 13 (KCTD13)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      190965073..190983381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)