U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Rhbdd3 rhomboid domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289753, updated on 3-Dec-2024

    Summary

    Official Symbol
    Rhbdd3provided by RGD
    Official Full Name
    rhomboid domain containing 3provided by RGD
    Primary source
    RGD:1311827
    See related
    EnsemblRapid:ENSRNOG00000027032 AllianceGenome:RGD:1311827
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311827
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to act upstream of or within several processes, including MAPK cascade; negative regulation of natural killer cell activation; and positive regulation of protein catabolic process. Predicted to be located in membrane. Orthologous to human RHBDD3 (rhomboid domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 167.0), Adrenal (RPKM 85.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rhbdd3 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (84208155..84214334)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (79994111..80000294)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (85350852..85357029)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene RAS-like, family 10, member A Neighboring gene growth arrest-specific 2 like 1 Neighboring gene EWS RNA-binding protein 1 Neighboring gene EMI domain containing 1 Neighboring gene kringle containing transmembrane protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    rhomboid domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013875.1NP_001013897.1  rhomboid domain-containing protein 3

      See identical proteins and their annotated locations for NP_001013897.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081912
      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
      Related
      ENSRNOP00000032424.4, ENSRNOT00000031914.7
      Conserved Domains (1) summary
      cl21463
      Location:326369
      UBA_like_SF; UBA domain-like superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      84208155..84214334
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006251207.4XP_006251269.1  rhomboid domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006251269.1

      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
      Conserved Domains (1) summary
      cl21463
      Location:326369
      UBA_like_SF; UBA domain-like superfamily
    2. XM_063272948.1XP_063129018.1  rhomboid domain-containing protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
    3. XM_006251205.4XP_006251267.1  rhomboid domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006251267.1

      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
      Conserved Domains (1) summary
      cl21463
      Location:326369
      UBA_like_SF; UBA domain-like superfamily
    4. XM_006251208.5XP_006251270.1  rhomboid domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006251270.1

      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
      Conserved Domains (1) summary
      cl21463
      Location:326369
      UBA_like_SF; UBA domain-like superfamily
    5. XM_039091740.2XP_038947668.1  rhomboid domain-containing protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
      Conserved Domains (1) summary
      cl21463
      Location:326369
      UBA_like_SF; UBA domain-like superfamily
    6. XM_039091738.2XP_038947666.1  rhomboid domain-containing protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
      Conserved Domains (1) summary
      cl21463
      Location:326369
      UBA_like_SF; UBA domain-like superfamily
    7. XM_006251204.5XP_006251266.1  rhomboid domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006251266.1

      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
      Conserved Domains (1) summary
      cl21463
      Location:326369
      UBA_like_SF; UBA domain-like superfamily
    8. XM_006251206.5XP_006251268.1  rhomboid domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006251268.1

      UniProtKB/Swiss-Prot
      Q642B3
      UniProtKB/TrEMBL
      A6IKK8
      Conserved Domains (1) summary
      cl21463
      Location:326369
      UBA_like_SF; UBA domain-like superfamily
    9. XM_063272949.1XP_063129019.1  rhomboid domain-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      A6IKK9