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    CG1529 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33077, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1529provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031144
    Locus tag
    Dmel_CG1529
    See related
    AllianceGenome:FB:FBgn0031144
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1529
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut primordium; gut section; hindgut proper primordium; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1529 in Genome Data Viewer
    Location:
    19E7-19E7; 1-65 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21028652..21031950, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20899679..20902977, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene ryder cup Neighboring gene uncharacterized protein Neighboring gene Nuclear transport factor-2 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44431 Neighboring gene Microsomal glutathione S-transferase-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sedentary Behavior Impacts on the Epigenome and Transcriptome: Lessons from Muscle Inactivation in Drosophila Larvae. Brener A, et al. Cells, 2023 Sep 22. PMID 37830547, Free PMC Article
    2. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    3. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
    4. Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. Telonis-Scott M, et al. J Insect Physiol, 2009 Jun. PMID 19232407
    5. Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations. Winbush A, et al. Genome Biol Evol, 2021 Jan 7. PMID 33247719, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1529-PA
    CG1529-PC
    CG1529-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      21028652..21031950 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144751.2 → NP_001138223.2  uncharacterized protein Dmel_CG1529, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138223.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z152
      Conserved Domains (4) summary
      sd00017
      Location:294 → 315
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:11 → 79
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam12756
      Location:201 → 257
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
      pfam15909
      Location:268 → 349
      zf-C2H2_8; C2H2-type zinc ribbon

    2. NM_134577.2 → NP_608421.1  uncharacterized protein Dmel_CG1529, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608421.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRT8, Q9VRD5
      Related
      FBpp0076959
      Conserved Domains (2) summary
      PRK09510
      Location:174 → 278
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      sd00017
      Location:77 → 98
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001298577.1 → NP_001285506.1  uncharacterized protein Dmel_CG1529, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285506.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z152
      Conserved Domains (4) summary
      sd00017
      Location:294 → 315
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:11 → 79
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam12756
      Location:201 → 257
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
      pfam15909
      Location:268 → 349
      zf-C2H2_8; C2H2-type zinc ribbon
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z152 B7Z152
    Q8MRT8 Q8MRT8
    Q9VRD5 Q9VRD5

    Gene LinkOut

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