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    dpr7 defective proboscis extension response 7 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 2768865, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dpr7provided by FlyBase
    Official Full Name
    defective proboscis extension response 7provided by FlyBase
    Primary source
    FLYBASE:FBgn0053481
    Locus tag
    Dmel_CG33481
    See related
    AllianceGenome:FB:FBgn0053481
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG33481; Dmel\CG33481; Dpr-7; Dpr7
    Summary
    Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dpr7 in Genome Data Viewer
    Location:
    102B1-102B1; 4-0 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (247124..253329, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (267750..273955, complement)

    Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46065 Neighboring gene yellow-h Neighboring gene uncharacterized protein Neighboring gene Rho GTPase activating protein at 102A Neighboring gene Nuclear factor I

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Affinity requirements for control of synaptic targeting and neuronal cell survival by heterophilic IgSF cell adhesion molecules. Xu S, et al. Cell Rep, 2022 Apr 5. PMID 35385751, Free PMC Article
    2. The KRÜPPEL-like transcription factor DATILÓGRAFO is required in specific cholinergic neurons for sexual receptivity in Drosophila females. Schinaman JM, et al. PLoS Biol, 2014 Oct. PMID 25291190, Free PMC Article
    3. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article
    4. Neural immunoglobulin superfamily interaction networks. Zinn K, et al. Curr Opin Neurobiol, 2017 Aug. PMID 28558267, Free PMC Article
    5. Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. Wang Y, et al. Development, 2022 May 15. PMID 35502740, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c248891-247471 mobile_element_type = transposon:Cr1a{}1621
    • Loc: c249443-249334 mobile_element_type = transposon:INE-1{}5360
    • Loc: c250683-250547 mobile_element_type = transposon:INE-1{}5314

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    defective proboscis extension response 7
    Names
    CG33481-PF
    CG33481-PG
    dpr7-PF
    dpr7-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.4 Reference assembly

      Range
      247124..253329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103380.3 → NP_001096850.2  defective proboscis extension response 7, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096850.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DZ27
      Conserved Domains (3) summary
      smart00410
      Location:179 → 265
      IG_like; Immunoglobulin like
      pfam07686
      Location:56 → 145
      V-set; Immunoglobulin V-set domain
      cl11960
      Location:187 → 257
      Ig; Immunoglobulin domain

    2. NM_001103381.3 → NP_001096851.2  defective proboscis extension response 7, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001096851.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DZ28
      Conserved Domains (3) summary
      smart00410
      Location:153 → 239
      IG_like; Immunoglobulin like
      pfam07686
      Location:30 → 119
      V-set; Immunoglobulin V-set domain
      cl11960
      Location:161 → 231
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8DZ27 A8DZ27
    A8DZ28 A8DZ28

    Gene LinkOut

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