Cyp12c1 Cytochrome P450 12c1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Cyp12c1provided by FlyBase
Official Full Name: Cytochrome P450 12c1provided by FlyBase
Primary source: FLYBASE:FBgn0036806
Locus tag: Dmel_CG4120
See related: AllianceGenome:FB:FBgn0036806
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 12c1; CG4120; Cyp12c; cyp12c1; Cyp12C1; Dmel\CG4120
Summary: Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in adult head; amnioserosa; and yolk nucleus. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bone disease (multiple); cerebrotendinous xanthomatosis; gastrointestinal system cancer (multiple); and lung cancer (multiple). Orthologous to human CYP24A1 (cytochrome P450 family 24 subfamily A member 1); CYP27A1 (cytochrome P450 family 27 subfamily A member 1); and CYP27B1 (cytochrome P450 family 27 subfamily B member 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (18684259..18686319, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (18677359..18679419, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info

NP_001287109.1

NP_649052.1

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The following sections contain reference sequences that belong to a specific genome build. Explain