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    dpr1 defective proboscis extension response 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 2768858, updated on 9-Dec-2024

    Summary

    Official Symbol
    dpr1provided by FlyBase
    Official Full Name
    defective proboscis extension response 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0040726
    Locus tag
    Dmel_CG13439
    See related
    AllianceGenome:FB:FBgn0040726
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13439; Dmel\CG13439; dpr; Dpr-1; Dpr1; DPR1
    Summary
    Involved in salt aversion; sensory perception of salty taste; and synapse organization. Located in plasma membrane. Is expressed in several structures, including amnioserosa anlage; anterior wing margin; ganglia; gustatory receptor neuron of the wing; and taste bristle. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See dpr1 in Genome Data Viewer
    Location:
    57B1-57B2; 2-92 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20698483..20750442)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16585988..16637947)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44660 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    mobile_element

    • Loc: 20739502-20744201 mobile_element_type = transposon:F{}863

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in salt aversion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sensory perception of salty taste IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 

    General protein information

    Preferred Names
    defective proboscis extension response 1
    Names
    CG13439-PA
    CG13439-PB
    defective proboscis extension response
    dpr1-PA
    dpr1-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20698483..20750442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206186.4NP_995908.2  defective proboscis extension response 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995908.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBY3, Q8T603
      Conserved Domains (3) summary
      cd00096
      Location:174244
      Ig; Immunoglobulin domain
      smart00410
      Location:60150
      IG_like; Immunoglobulin like
      cl11960
      Location:59154
      Ig; Immunoglobulin domain
    2. NM_001299716.1NP_001286645.1  defective proboscis extension response 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286645.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBY3, Q8T603
      Conserved Domains (3) summary
      cd00096
      Location:174244
      Ig; Immunoglobulin domain
      smart00410
      Location:60150
      IG_like; Immunoglobulin like
      cl11960
      Location:59154
      Ig; Immunoglobulin domain