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    CG12104 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38187, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12104provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035238
    Locus tag
    Dmel_CG12104
    See related
    AllianceGenome:FB:FBgn0035238
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12104
    Summary
    Is expressed in several structures, including embryonic proventriculus inner layer; gut section; male germline cell; posterior midgut primordium; and proventriculus anlage. Orthologous to several human genes including TOX (thymocyte selection associated high mobility group box). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12104 in Genome Data Viewer
    Location:
    62A7-62A7; 3-0.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1600726..1602674, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1600726..1602674, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Transmembrane endosomal protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45814 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The HMG-box-containing proteins tHMG-1 and tHMG-2 interact during the histone-to-protamine transition in Drosophila spermatogenesis. Gärtner SM, et al. Eur J Cell Biol, 2015 Jan. PMID 25464903
    2. Identification of germ plasm-enriched mRNAs in Drosophila melanogaster by the cDNA microarray technique. Szuperák M, et al. Gene Expr Patterns, 2005 Jun. PMID 15939385
    3. A Testis-Specific Chaperone and the Chromatin Remodeler ISWI Mediate Repackaging of the Paternal Genome. Doyen CM, et al. Cell Rep, 2015 Nov 17. PMID 26549447
    4. Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases. Kline RA, et al. PLoS Genet, 2017 Mar. PMID 28362802, Free PMC Article
    5. The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. Zhou S, et al. Environ Health Perspect, 2016 Jul. PMID 26859824, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12104-PA
    CG12104-PB
    CG12104-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1600726..1602674 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274338.1 → NP_001261267.1  uncharacterized protein Dmel_CG12104, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261267.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0D2
      Conserved Domains (1) summary
      cd00084
      Location:76 → 140
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...

    2. NM_139372.3 → NP_647629.1  uncharacterized protein Dmel_CG12104, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647629.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0D2
      Related
      FBpp0072705
      Conserved Domains (1) summary
      cd00084
      Location:76 → 140
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...

    3. NM_001299971.1 → NP_001286900.1  uncharacterized protein Dmel_CG12104, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286900.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JG46
      Conserved Domains (1) summary
      cd00084
      Location:52 → 116
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W0D2 Q9W0D2
    X2JG46 X2JG46

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