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    CG13920 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38203, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13920provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0025712
    Locus tag
    Dmel_CG13920
    See related
    AllianceGenome:FB:FBgn0025712
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:CK00246; CK00246; Dmel\CG13920; NACHO
    Summary
    Predicted to be involved in chaperone-mediated protein complex assembly and positive regulation of protein localization to cell surface. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including adult head; adult heart; central brain primordium; embryonic central brain neurons; and ganglia. Orthologous to human TMEM35A (transmembrane protein 35A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13920 in Genome Data Viewer
    Location:
    62A9-62A9; 3-0.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1648944..1651501)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1648635..1651501)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45815 Neighboring gene Brother Neighboring gene Vesicle trafficking 1 Neighboring gene uncharacterized protein Neighboring gene Serine-arginine repetitive matrix 2/3/4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Agonist and antagonist properties of an insect GABA-gated chloride channel (RDL) are influenced by heterologous expression conditions. Smelt CLC, et al. PLoS One, 2021. PMID 34234379, Free PMC Article
    2. Cholinergic Synaptic Homeostasis Is Tuned by an NFAT-Mediated α7 nAChR-K(v)4/Shal Coupled Regulatory System. Eadaim A, et al. Cell Rep, 2020 Sep 8. PMID 32905767, Free PMC Article
    3. A high throughput screen to identify secreted and transmembrane proteins involved in Drosophila embryogenesis. Kopczynski CC, et al. Proc Natl Acad Sci U S A, 1998 Aug 18. PMID 9707585, Free PMC Article
    4. Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Dutta D, et al. Proc Natl Acad Sci U S A, 2024 Feb 27. PMID 38381787, Free PMC Article
    5. Post-transcriptional repression of the Drosophila midkine and pleiotrophin homolog miple by HOW is essential for correct mesoderm spreading. Toledano-Katchalski H, et al. Development, 2007 Oct. PMID 17728343

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in chaperone-mediated protein complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of protein localization to cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13920-PA
    CG13920-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1648944..1651501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299973.1 → NP_001286902.1  uncharacterized protein Dmel_CG13920, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286902.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0T9, Q9W0B4
      Conserved Domains (1) summary
      pfam13564
      Location:13 → 131
      DoxX_2; DoxX-like family

    2. NM_139382.4 → NP_647639.1  uncharacterized protein Dmel_CG13920, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647639.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0T9, Q9W0B4
      Related
      FBpp0072644
      Conserved Domains (1) summary
      pfam13564
      Location:13 → 131
      DoxX_2; DoxX-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T0T9 Q8T0T9

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