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    CG6870 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35067, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6870provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032652
    Locus tag
    Dmel_CG6870
    See related
    AllianceGenome:FB:FBgn0032652
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6870
    Summary
    Predicted to enable heme binding activity. Predicted to be involved in sterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle and membrane. Is expressed in amnioserosa; embryonic/larval fat body; eye; fat body/gonad primordium; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6870 in Genome Data Viewer
    Location:
    36D1-36D1; 2-53 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (17591315..17592299, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (17591315..17592299, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44411 Neighboring gene long non-coding RNA:CR44410 Neighboring gene Olig family Neighboring gene Synaptotagmin alpha Neighboring gene long non-coding RNA:CR44412 Neighboring gene long non-coding RNA:CR44413

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila lacks C20 and C22 PUFAs. Shen LR, et al. J Lipid Res, 2010 Oct. PMID 20656917, Free PMC Article
    2. Drosophila larvae fed palm fruit juice (PFJ) delay pupation via expression regulation of hormetic stress response genes linked to ageing and longevity. Leow SS, et al. Exp Gerontol, 2018 Jun. PMID 29550564
    3. Regulation of locomotion and motoneuron trajectory selection and targeting by the Drosophila homolog of Olig family transcription factors. Oyallon J, et al. Dev Biol, 2012 Sep 15. PMID 22796650, Free PMC Article
    4. Comparative transcriptional profiling identifies takeout as a gene that regulates life span. Bauer J, et al. Aging (Albany NY), 2010 May. PMID 20519778, Free PMC Article
    5. Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease. Scherzer CR, et al. Hum Mol Genet, 2003 Oct 1. PMID 12915459

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sterol biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6870-PA
    CG6870-PB
    cytochrome B5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      17591315..17592299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299089.1 → NP_001286018.1  uncharacterized protein Dmel_CG6870, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286018.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJC0
      Conserved Domains (1) summary
      pfam00173
      Location:46 → 116
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

    2. NM_136008.4 → NP_609852.1  uncharacterized protein Dmel_CG6870, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609852.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJC0
      Related
      FBpp0080542
      Conserved Domains (1) summary
      pfam00173
      Location:46 → 116
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VJC0 Q9VJC0

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