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    PpY-55A Protein phosphatase Y at 55A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 48532, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PpY-55Aprovided by FlyBase
    Official Full Name
    Protein phosphatase Y at 55Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003140
    Locus tag
    Dmel_CG10930
    See related
    AllianceGenome:FB:FBgn0003140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10930; D19; Dmel\CG10930; DmPpY-55A; PpD19; PPY; PPY 55A
    Summary
    Enables protein serine/threonine phosphatase activity. Located in cytoplasm and nucleus. Is expressed in cyst cell of testis; primary spermatocyte; and testis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See PpY-55A in Genome Data Viewer
    Location:
    55A2-55A2; 2-84 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17955396..17956570, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13842901..13844075, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Eag-like K[+] channel Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44418 Neighboring gene defective proboscis extension response 13 Neighboring gene long non-coding RNA:CR44419 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and chromosomal localization of a novel Drosophila protein phosphatase. Dombrádi V, et al. FEBS Lett, 1989 Apr 24. PMID 2541022
    2. Drosophila PPY, a novel male specific protein serine/threonine phosphatase localised in somatic cells of the testis. Armstrong CG, et al. J Cell Sci, 1995 Nov. PMID 8586649
    3. Germ line specific expression of a protein phosphatase Y interacting protein (PPYR1) in Drosophila. Kókai E, et al. Gene Expr Patterns, 2006 Oct. PMID 16530491
    4. CG15031/PPYR1 is an intrinsically unstructured protein that interacts with protein phosphatase Y. Kókai E, et al. Arch Biochem Biophys, 2006 Jul 1. PMID 16631104
    5. Characterisation of a novel Drosophila melanogaster testis specific PP1 inhibitor related to mammalian inhibitor-2: identification of the site of interaction with PP1. Helps NR, et al. FEBS Lett, 1998 Oct 30. PMID 9821974

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase Y at 55A
    Names
    CG10930-PA
    CG10930-PB
    PpY-55A-PA
    PpY-55A-PB
    protein phosphatase D19
    protein phosphatase from PCR fragment D19
    protein phosphatase-Y
    NP_001286554.1
    NP_476689.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17955396..17956570 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057341.4 → NP_476689.1  protein phosphatase Y at 55A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476689.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P11612, Q26247, Q9V8A0
      UniProtKB/TrEMBL
      A0A0B4LFR7
      Related
      FBpp0085996
      Conserved Domains (2) summary
      PTZ00480
      Location:8 → 310
      PTZ00480; serine/threonine-protein phosphatase; Provisional
      cd07414
      Location:8 → 294
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain

    2. NM_001299625.1 → NP_001286554.1  protein phosphatase Y at 55A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286554.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P11612, Q26247, Q9V8A0
      UniProtKB/TrEMBL
      A0A0B4LFR7
      Conserved Domains (2) summary
      PTZ00480
      Location:8 → 310
      PTZ00480; serine/threonine-protein phosphatase; Provisional
      cd07414
      Location:8 → 294
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LFR7 A0A0B4LFR7
    P11612.2 P11612

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