Cep89 Centrosomal protein 89kDa [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Cep89provided by FlyBase
Official Full Name: Centrosomal protein 89kDaprovided by FlyBase
Primary source: FLYBASE:FBgn0266708
Locus tag: Dmel_CG8214
See related: AllianceGenome:FB:FBgn0266708
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: cep89; CEP89; CG8214; Dmel\CG8214
Summary: Involved in several processes, including chemical synaptic transmission; habituation; and non-motile cilium assembly. Part of ciliary transition fiber. Is expressed in Johnston organ; antennal segment 3 sense organ; scolopidial cilium; spermatid; and spermatocyte. Used to study cytochrome-c oxidase deficiency disease and neurodegenerative disease. Orthologous to human CEP89 (centrosomal protein 89). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (15687388..15688985, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (11574893..11576490, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	IEA Inferred from Electronic Annotation more info
involved_in mitochondrion organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrion organization	IEA Inferred from Electronic Annotation more info
involved_in mitochondrion organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in non-motile cilium assembly	IGI Inferred from Genetic Interaction more info	PubMed
involved_in non-motile cilium assembly	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in centriole	IBA Inferred from Biological aspect of Ancestor more info
located_in centriole	IEA Inferred from Electronic Annotation more info
part_of ciliary transition fiber	IBA Inferred from Biological aspect of Ancestor more info
part_of ciliary transition fiber	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrial intermembrane space	ISS Inferred from Sequence or Structural Similarity more info

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