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    CG10062 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37224, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10062provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034439
    Locus tag
    Dmel_CG10062
    See related
    AllianceGenome:FB:FBgn0034439
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.226; Dmel\CG10062
    Summary
    Predicted to enable metalloexopeptidase activity. Predicted to be involved in proteolysis. Is expressed in adult head. Orthologous to human ERMP1 (endoplasmic reticulum metallopeptidase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10062 in Genome Data Viewer
    Location:
    56D2-56D2; 2-89 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19375313..19380174)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15262818..15267679)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling. Erkosar B, et al. PLoS One, 2014. PMID 24733183, Free PMC Article
    2. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    3. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article
    4. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metalloexopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10062-PA
    CG10062-PC
    CG10062-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19375313..19380174
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274160.1 → NP_001261089.1  uncharacterized protein Dmel_CG10062, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261089.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEU8, C7LAC3
      Conserved Domains (1) summary
      cd03875
      Location:59 → 364
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1

    2. NM_137572.4 → NP_611416.2  uncharacterized protein Dmel_CG10062, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611416.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBK3, C7LAC3
      Related
      FBpp0085710
      Conserved Domains (1) summary
      cd03875
      Location:59 → 364
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1

    3. NM_001169731.2 → NP_001163202.2  uncharacterized protein Dmel_CG10062, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163202.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JGM3, Q7K0K8
      Conserved Domains (1) summary
      cd03875
      Location:17 → 322
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KEU8 A0A0B4KEU8
    A1ZBK3 A1ZBK3
    E1JGM3 E1JGM3
    Q7K0K8 Q7K0K8

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