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    CG12134 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36038, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12134provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033471
    Locus tag
    Dmel_CG12134
    See related
    AllianceGenome:FB:FBgn0033471
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CKIalpha like; Dmel\CG12134
    Summary
    Is expressed in embryonic/larval midgut; larval muscle system; and organism. Orthologous to human WDR89 (WD repeat domain 89). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12134 in Genome Data Viewer
    Location:
    46C9-46C9; 2-61 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9971143..9972780)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5858648..5860285)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 3 subunit j Neighboring gene antisense RNA:CR46453 Neighboring gene long non-coding RNA:CR46455 Neighboring gene antisense RNA:CR43948 Neighboring gene even skipped

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans. Fujioka M, et al. PLoS Genet, 2016 Feb. PMID 26910731, Free PMC Article
    2. Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains. Van Bortle K, et al. Genome Res, 2012 Nov. PMID 22722341, Free PMC Article
    3. Sepsid even-skipped enhancers are functionally conserved in Drosophila despite lack of sequence conservation. Hare EE, et al. PLoS Genet, 2008 Jun 27. PMID 18584029, Free PMC Article
    4. A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease. Nim HT, et al. Genome Biol, 2021 Dec 15. PMID 34906219, Free PMC Article
    5. Mechanisms of Interaction between Enhancers and Promoters in Three Drosophila Model Systems. Kyrchanova O, et al. Int J Mol Sci, 2023 Feb 2. PMID 36769179, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12134-PA
    CG12134-PC
    CG12134-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      9971143..9972780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136698.3 → NP_610542.1  uncharacterized protein Dmel_CG12134, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610542.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JRI4, Q7JZ37
      Related
      FBpp0087476
      Conserved Domains (2) summary
      sd00039
      Location:59 → 101
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:56 → 384
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001382018.1 → NP_001368943.1  uncharacterized protein Dmel_CG12134, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z827, Q7JRI4
      Conserved Domains (2) summary
      sd00039
      Location:58 → 100
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:55 → 383
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_001382019.1 → NP_001369072.1  uncharacterized protein Dmel_CG12134, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JRI4, Q7JZ37
      Conserved Domains (2) summary
      sd00039
      Location:59 → 101
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:56 → 384
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z827 A1Z827
    Q7JRI4 Q7JRI4
    Q7JZ37 Q7JZ37

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