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    mTerf5 mitochondrial transcription termination factor 5 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42182, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mTerf5provided by FlyBase
    Official Full Name
    mitochondrial transcription termination factor 5provided by FlyBase
    Primary source
    FLYBASE:FBgn0038584
    Locus tag
    Dmel_CG7175
    See related
    AllianceGenome:FB:FBgn0038584
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7175; D-MTERF5; Dmel\CG7175
    Summary
    Predicted to enable nucleic acid binding activity. Involved in mitochondrial transcription. Located in mitochondrion. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mTerf5 in Genome Data Viewer
    Location:
    90F7-90F8; 3-62 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18221522..18223682, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14047244..14049404, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Novel nucleolar protein 3 Neighboring gene uncharacterized protein Neighboring gene Malate dehydrogenase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial transcription terminator family members mTTF and mTerf5 have opposing roles in coordination of mtDNA synthesis. Jõers P, et al. PLoS Genet, 2013. PMID 24068965, Free PMC Article
    2. MTERF3, the most conserved member of the mTERF-family, is a modular factor involved in mitochondrial protein synthesis. Roberti M, et al. Biochim Biophys Acta, 2006 Sep-Oct. PMID 16787637
    3. D-MTERF5 is a novel factor modulating transcription in Drosophila mitochondria. Bruni F, et al. Mitochondrion, 2012 Sep. PMID 22784680, Free PMC Article
    4. Mitochondrial DNA maintenance in Drosophila melanogaster. Rodrigues APC, et al. Biosci Rep, 2022 Nov 30. PMID 36254835, Free PMC Article
    5. Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase. Fukuoh A, et al. Mol Syst Biol, 2014 Jun 21. PMID 24952591, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in termination of mitochondrial transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial transcription termination factor 5
    Names
    CG7175-PA
    mTerf5-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18221522..18223682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142436.4 → NP_650693.1  mitochondrial transcription termination factor 5 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650693.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VEB4
      Related
      FBpp0083029
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VEB4.1 Q9VEB4

    Gene LinkOut

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