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    JTBR JTBR [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38235, updated on 9-Dec-2024

    Summary

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    Official Symbol
    JTBRprovided by FlyBase
    Official Full Name
    JTBRprovided by FlyBase
    Primary source
    FLYBASE:FBgn0025820
    Locus tag
    Dmel_CG1935
    See related
    AllianceGenome:FB:FBgn0025820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:fe2G4; BcDNA:RH07980; CG1935; dJTB-like; dJTBR; Dmel\CG1935
    Summary
    Predicted to be involved in mitotic cytokinesis. Predicted to be located in membrane. Predicted to be active in cytoplasm and midbody. Predicted to colocalize with centrosome and spindle. Is expressed in adult head and organism. Orthologous to human JTB (jumping translocation breakpoint). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See JTBR in Genome Data Viewer
    Location:
    62B4-62B4; 3-1.0 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1802008..1802856, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1802008..1802856, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cell division cycle 37 Neighboring gene antisense RNA:CR45818 Neighboring gene uncharacterized protein Neighboring gene patj Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45686 Neighboring gene long non-coding RNA:CR45687

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Domain-specific early and late function of Dpatj in Drosophila photoreceptor cells. Nam SC, et al. Dev Dyn, 2006 Jun. PMID 16518799
    2. A set of structural features defines the cis-regulatory modules of antenna-expressed genes in Drosophila melanogaster. López Y, et al. PLoS One, 2014. PMID 25153327, Free PMC Article
    3. A screen for fast evolving genes from Drosophila. Schmid KJ, et al. Proc Natl Acad Sci U S A, 1997 Sep 2. PMID 9275195, Free PMC Article
    4. Generation of LexA enhancer-trap lines in Drosophila by an international scholastic network. Kim ES, et al. G3 (Bethesda), 2023 Aug 30. PMID 37279923, Free PMC Article
    5. Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED. Hadžić T, et al. Nucleic Acids Res, 2015 Feb 27. PMID 25634895, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    colocalizes_with spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    JTBR
    Names
    CG1935-PA
    CG1935-PB
    CG1935-PC
    JTBR-PA
    JTBR-PB
    JTBR-PC
    anon-fast-evolving-2G4
    jumping translocation breakpoint

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1802008..1802856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274360.1 → NP_001261289.1  JTBR, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261289.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O96067, Q8SXQ3
      Conserved Domains (1) summary
      pfam05439
      Location:40 → 148
      JTB; Jumping translocation breakpoint protein (JTB)

    2. NM_001274361.1 → NP_001261290.1  JTBR, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261290.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O96067, Q8SXQ3
      Conserved Domains (1) summary
      pfam05439
      Location:40 → 148
      JTB; Jumping translocation breakpoint protein (JTB)

    3. NM_058055.5 → NP_477403.1  JTBR, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477403.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O96067, Q8SXQ3
      Related
      FBpp0072671
      Conserved Domains (1) summary
      pfam05439
      Location:40 → 148
      JTB; Jumping translocation breakpoint protein (JTB)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O96067 O96067
    Q8SXQ3 Q8SXQ3

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