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    CG11275 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37534, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11275provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034706
    Locus tag
    Dmel_CG11275
    See related
    AllianceGenome:FB:FBgn0034706
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11275; i188
    Summary
    Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including adult fat body; antennal primordium; clypeo-labral primordium; gut section; and head epidermis primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11275 in Genome Data Viewer
    Location:
    58C5-58C5; 2-98 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22179695..22182642)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18067200..18070147)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45151 Neighboring gene F-box protein 42 Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene Mediator complex subunit 16 Neighboring gene Vacuolar protein sorting 35 Neighboring gene Secreted Wg-interacting molecule

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide analysis reveals a major role in cell fate maintenance and an unexpected role in endoreduplication for the Drosophila FoxA gene Fork head. Maruyama R, et al. PLoS One, 2011. PMID 21698206, Free PMC Article
    2. Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition. Fan W, et al. PLoS Genet, 2017 Mar. PMID 28273089, Free PMC Article
    3. Identifying candidate genes affecting developmental time in Drosophila melanogaster: pervasive pleiotropy and gene-by-environment interaction. Mensch J, et al. BMC Dev Biol, 2008 Aug 8. PMID 18687152, Free PMC Article
    4. A Gene Expression Screen in Drosophila melanogaster Identifies Novel JAK/STAT and EGFR Targets During Oogenesis. Wittes J, et al. G3 (Bethesda), 2019 Jan 9. PMID 30385460, Free PMC Article
    5. Isolation of proteins that interact with the signal transduction molecule Dof and identification of a functional domain conserved between Dof and vertebrate BCAP. Battersby A, et al. J Mol Biol, 2003 Jun 6. PMID 12767830

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11275-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22179695..22182642
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137805.3 → NP_611649.1  uncharacterized protein Dmel_CG11275 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611649.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V5D1, Q9W279
      Related
      FBpp0071683
      Conserved Domains (2) summary
      smart00225
      Location:33 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 122
      BTB; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W279 Q9W279

    Gene LinkOut

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