MED18 Mediator complex subunit 18 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: MED18provided by FlyBase
Official Full Name: Mediator complex subunit 18provided by FlyBase
Primary source: FLYBASE:FBgn0026873
Locus tag: Dmel_CG14802
See related: AllianceGenome:FB:FBgn0026873
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG14802; Dmel\CG14802; dp28b; EG:63B12.13; Med18; p28; p28/CG14802; Srb5/Med28b
Summary: Enables transcription coregulator activity. Involved in regulation of transcription by RNA polymerase II. Located in nucleus. Part of mediator complex. Orthologous to human MED18 (mediator complex subunit 18). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (1865909..1866887)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (1759942..1760920)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
contributes_to transcription coregulator activity	IC Inferred by Curator more info	PubMed
enables transcription coregulator activity	IEA Inferred from Electronic Annotation more info
enables transcription coregulator activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of transcription initiation by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IC Inferred by Curator more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of core mediator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mediator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mediator complex	IDA Inferred from Direct Assay more info	PubMed
part_of mediator complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed