U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Mon1 Monensin sensitivity 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33689, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mon1provided by FlyBase
    Official Full Name
    Monensin sensitivity 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0031640
    Locus tag
    Dmel_CG11926
    See related
    AllianceGenome:FB:FBgn0031640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11926; Dmel\CG11926; dMon1; Dmon1; mon1; MON1; NP_608868
    Summary
    Enables guanyl nucleotide exchange factor inhibitor activity. Contributes to guanyl-nucleotide exchange factor activity. Involved in endosome to lysosome transport via multivesicular body sorting pathway and neuromuscular junction development. Located in cytosol and synaptic cleft. Part of Mon1-Ccz1 complex. Is expressed in adult head. Orthologous to several human genes including MON1A (MON1 homolog A, secretory trafficking associated). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Mon1 in Genome Data Viewer
    Location:
    25B1-25B1; 2-14 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4850641..4852640)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4850641..4852640)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene mextli Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein S2 Neighboring gene smog Neighboring gene Chorion factor 2

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    part_of Mon1-Ccz1 complex  
    part_of Mon1-Ccz1 complex PubMed 
    part_of Mon1-Ccz1 complex  
    located_in cytosol PubMed 
    located_in synaptic cleft PubMed 

    General protein information

    Preferred Names
    monensin sensitivity 1
    Names
    CG11926-PA
    Mon1 ortholog
    Mon1-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4850641..4852640
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135024.2 → NP_608868.1  monensin sensitivity 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608868.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VR38
      UniProtKB/TrEMBL
      Q8MRZ0
      Related
      FBpp0077079
      Conserved Domains (1) summary
      pfam03164
      Location:115 → 527
      Mon1; Trafficking protein Mon1
    External link. Please review our privacy policy.